甘氨胆酸抗炎作用的研究  

STUDIES ON ANTI-INFLAMMATION ACTIONS OF GLYCOCHOLIC ACID

作　　者：李慧峰[1] 李培锋[1] 关红[1] 李玉娟[2] 王殿柱[3] 

机构地区：[1]内蒙古农业大学动物科学与医学学院,呼和浩特010018 [2]包头农牧学校,包头014300 [3]包头市农垦集团,包头014300

出　　处：《内蒙古农业大学学报（自然科学版）》2006年第2期5-8,共4页Journal of Inner Mongolia Agricultural University(Natural Science Edition)

基　　金：内蒙古自治区人才基金项目

摘　　要：目的:研究甘氨胆酸的抗炎作用。方法:采用小鼠耳廓肿胀法、皮内染料渗出法、甲醛和琼脂所致大鼠足跖肿胀法以及棉球肉芽肿胀法,观察甘氨胆酸的急慢性炎症反应。结果:高、低剂量的甘氨胆酸对二甲苯所致小鼠耳廓肿胀和小鼠皮肤毛细血管通透性,棉球所致小鼠肉芽肿,甲醛所致大鼠足跖肿胀以及琼脂所致大鼠足跖肿胀均有显著抑制作用。结论:甘氨胆酸对急性和慢性炎症均有显著的抑制作用。Anti - inflammatory actions of GCA was studied. The acute - inflammation was examined in rats whose auricles and intracutaneous suffered from xylene respectively and mice whose planters swelling was induced by formaldehyde and agar. The chronical - inflammation was examined in rats whose granuloma was induced by implanting cutton ball. GCA had significant effcts on the acute - inflammation and chronical - inflammation.

关 键 词：胆汁 甘氨胆酸 抗炎作用 

分 类 号：S859.4[农业科学—临床兽医学]