心力衰竭合并睡眠呼吸暂停发生情况和临床特点  

High Prevalence and Clinical Characteristics of Sleep Apnea in Chinese Inpatients With Congestive Heart Failure

作　　者：赵智慧[1] 柳志红[1] 罗勤[1] 张健[2] 熊长明 倪新海[1] 张澍[3] 杨跃进[2] 马秀平[1] 

机构地区：[1]中国医学科学院中国协和医科大学心血管病研究所阜外心血管病医院肺血管病诊治中心,北京市100037 [2]中国医学科学院中国协和医科大学心血管病研究所阜外心血管病医院冠心病诊治中心,北京市100037 [3]中国医学科学院中国协和医科大学心血管病研究所阜外心血管病医院心律失常诊治中心,北京市100037

出　　处：《中国循环杂志》2006年第3期190-192,共3页Chinese Circulation Journal

基　　金：(20032011)首都医学发展院所青年基金资助课题

摘　　要：目的:了解心力衰竭(心衰)患者合并睡眠呼吸暂停发生情况和临床特点。方法:对符合入选标准的126例心衰患者以睡眠呼吸暂停低通气指数(AHI)≥10为界值,分为心衰合并睡眠呼吸暂停组和心衰不合并睡眠呼吸暂停组,进行病史采集及多普勒超声心动图、睡眠呼吸监测等。结果:90例心衰合并睡眠呼吸暂停组中有32例(36％)为心衰合并阻塞性睡眠呼吸暂停,58例(64％)为心衰合并中枢性睡眠呼吸暂停。心衰合并睡眠呼吸暂停组较不合并睡眠呼吸暂停组睡眠呼吸暂停低通气指数、血氧饱和度、低氧指数和鼾声指数均有显著性差异(P<0．05-0．001)。结论:心衰患者合并睡眠呼吸暂停较常见,肥胖、习惯性打鼾、高血压病史和夜尿次数增多者易合并睡眠呼吸暂停。习惯性打鼾、高血压病史和夜尿次数增多是心力衰竭患者合并睡眠呼吸暂停的独立危险因素。Objective： To determine the prevalence and clinical features of sleep apnea （SA） in patients with congestive heart failure （ CHF）. Methods ： Data were collected on medical history, Doppler echocardiography and sleep monitoring in 126 eligible consecutive patients with CHF classified as New York Heart Association [ NYHA] class Ⅱ-Ⅳ or left ventricular ejection fraction ≤0. 45. Results： There were 71% of CHF patients with SA. The patients had a remarkable lower minimum arterial oxyhemoglobin saturation （ P 〈 0. 001 ） and a mean arterial oxyhemoglobin saturation （ P 〈 0.01 ）. Habitual snoring, history of hypertension, frequent nocturia were independent risks for SA patients with CHF. Conclusions ： The prevalence of CHF patients with SA is high, CHF patients with obesity, snoring, history of hypertension and frequent nocturia are liable to develop SA.

关 键 词：心力衰竭 睡眠呼吸暂停 

分 类 号：R541[医药卫生—心血管疾病]