精子形态与精子运动参数关系研究  

Relationship between Sperm Motility Parameters and Sperm Morphology

作　　者：马玉涵[1] 刘睿智[2] 许宗革[2] 张红国[3] 李哲[2] 

机构地区：[1]华中师范大学生命科学学院,湖北武汉430079 [2]吉林大学基础医学院细胞生物学教研室,吉林长春130021 [3]东北师范大学遗传与细胞研究所,吉林长春130024

出　　处：《中华男科学杂志》2006年第7期590-593,共4页National Journal of Andrology

基　　金：吉林省科技厅资助项目(20030433)

摘　　要：目的:探讨精子形态与精子运动参数关系。方法:783例不育患者,采用精子自动分析系统分析精子运动参数,采用精子形态检测系统下人工修正方法进行精子形态分析。精子形态正常组241例,异常组542例。结果:精子形态异常组精子曲线速度(VCL)、摆动性(WOB)、平均路径速度(VAP)均显著高于精子形态正常组(P<0.05,P<0.001),而精子形态异常组精子平均移动角度(MAD)、直线性(LIN)、前向性(STR)均显著低于精子形态正常组(P<0.05,P<0.001);形态正常精子百分率与MAD、LIN、WOB、STR有显著正相关性,而与侧摆幅度(ALH)有显著负相关。结论:精子形态异常和运动能力弱相伴产生,形态异常对精子运动的影响可能只是这一现象产生的次要原因,而一些共同作用于精子形态和运动能力的因素也许是导致这一现象产生的主要原因。Objective： To evaluate the relationship between sperm motility parameters and sperm morphology. Methods： Seven hundred and eighty-three semen samples were tested. Sperm motility parameters were analyzed by computer-alded sperm analysis （CASA）, and sperm morphology assessed by automated sperm morphology analyzer（ASMA）. The cases were classified based on the World Health Organization criteria. Morphologically 241 of the samples were normal and the other 542 abnormal. Results： VCL, WOB, VAP of the morphologically abnormal group were significantly higher than those of the normal group （ P 〈 0.05, P 〈 0.001 ）, while MAD, LIN, STR of the abnormal group were significantly lower （ P 〈 0.05, P 〈 0.001 ）. There were significant positive correlations between the morphologically normal sperm rates and MAD, LIN, WOB, STR, and a significant negative correlation between the morphologically normal sperm rate and ALH. Conclusion ： Morphological abnormality of sperm is often accompanied with weak motility, which is probably attributed more to some factors .that coact on beth sperm motility and morphology than to the influence of sperm morphological abnormality on sperm motility.

关 键 词：男性不育 精子形态 精子运动参数 

分 类 号：R698.2[医药卫生—泌尿科学]