猪水肿病发病机理研究进展  

Progress on Pathogenesis of Edema Disease of Swine

作　　者：林艺远[1] 刘国平[1] 杨明柳[1] 吴斌[1] 

机构地区：[1]华中农业大学动物医学院动物病毒室,湖北武汉430070

出　　处：《动物医学进展》2006年第7期10-15,共6页Progress In Veterinary Medicine

基　　金：湖北省科技攻关计划项目(2001AA201)

摘　　要：猪水肿病主要发生于断奶后2周内的仔猪,是常见的一种急性致死性传染病。该病是由利用其菌毛(F18ab)黏附于小肠上皮细胞,并产生类志贺样毒素Ⅱ型变异体(SLT-Ⅱe)的产类志贺毒素大肠埃希菌引起的一种肠毒血症。仔猪断奶后的免疫能力,营养水平和遗传抗性是导致猪水肿病的主要影响因素。文章着重阐述了猪水肿病的致病机理,为该病的预防和治疗提供重要的理论依据。Edema disease of swine（ED） is a common cause of severe illness and death loss in pigs during the first 2 weeks after weaning. The disease is an enterotoxemia caused by Shiga-like toxin Escherichia coli （SLTEC） that colonize the small intestine epithelial cell by fimbriae F18ab and produce SLT- Ⅱe. Suscep- tibility of piglets to disease depends on several factors, especially on immunity, diet and genetic resistance after weaning. In this paper,the emphasis is focused on the pathogenesis which is a complicated process in order to offer the important theoretical basis to preventive and therapeutic measures to the disease.

关 键 词：猪水肿病 产类志贺毒素大肠埃希菌 致病机理 

分 类 号：S852.612[农业科学—基础兽医学] S858.28[农业科学—兽医学]