肥胖儿童并发症及综合干预20例疗效观察  

Observation on the effect of comprehensive therapy in the complication of 20 obesity children.

作　　者：容桃[1] 黄飘[1] 陈英女[1] 郭建波[1] 

机构地区：[1]化州市人民医院,广东化州525100

出　　处：《齐鲁护理杂志》2006年第07A期1201-1202,共2页Journal of Qilu Nursing

摘　　要：目的:了解单纯性肥胖儿胰岛素抵抗、脂肪肝及其他并发症的发生情况,观察综合干预治疗对控制肥胖儿体重的效果。方法:对40例单纯性肥胖儿做糖耐量及胰岛素释放试验,检测血脂、血清瘦素、肝肾功能,随机分为两组各20例,干预组给予饮食、运动、药物等综合干预治疗。结果:本组血清瘦素均升高,血甘油三酯升高6例、基础胰岛素增高11例、胰岛素抵抗指数(IR)增高10例、脂肪肝18例,黑棘皮病13例。干预组体重、腰围、体重指数均明显降低,差异有显著性。结论:儿童肥胖者与高瘦素血症、胰岛素抵抗及脂肪肝发病相关,综合干预治疗对控制肥胖者体重有重要意义。Objective： To investigate the symptoms of insulin resistance,fatty liver and other complications in obesity children and observe the effect of comprehensive therapy. Methods： The glucose tolerance test and insulin releasing test ,the function of liver and renal were determined,the serum levels of blood lipid and leptin were detected in 40 obesity children. The patients were divided into two groups at random. The intervention group （n = 20） were treated with sports, diet and drugs. Results- The concentration of leptin were all increased, the serum levels of triglyceride,basic in- sulin and IR were all increased,respectively 6 cases, 11 cases and10 cases. There were18 fatty liver, 13 acanthoma nigricans. The body weight ,waist,body mass index in the intervention group were more reduced significantly after treatment. Conclusion： It is relationship between high leptin, IR and fatty liver in obesity children, comprehensive therapy is of great significance to control the body weight in obesity children.

关 键 词：肥胖症 瘦素 胰岛素抵抗 

分 类 号：R473.72[医药卫生—护理学]