肾移植术后近期脑梗死危险因素分析  

Risk factors of cerebral embolism in kidney transplantation recipients

作　　者：苗书斋[1] 邢利[1] 李玉华[1] 蔡文利[1] 曲青山[1] 

机构地区：[1]河南省郑州市第五人民医院器官移植科,郑州450003

出　　处：《中原医刊》2006年第15期26-27,共2页Central Plains Medical Journal

摘　　要：目的探讨肾移植术后患者近期发生脑梗死的危险因素。方法13例肾移植术后近期发生脑梗死的患者,回顾性分析其移植前及移植后第1、2、3个月的平均血压、空腹血糖、总胆固醇、甘油三酯、血肌酐水平以及环孢素(CsA)或他可莫司(FK506)浓度。结果肾移植术后患者血脂和血糖均明显升高(P<0.05),肾移植术后脑梗死患者血肌酐水平较术前明显降低(P<0.05),平均血压水平与手术后3个月比较差异无统计学意义(P>0.05)。结论影响近期肾移植术后病人发生脑梗死的主要危险因素是肾功能,空腹血糖以及血脂水平;且血糖、总胆固醇、甘油三酯水平和CsA或FK506浓度有相关性。Obiective To analyze the risk factors for cerebral embolism in kidney transplantation recipients. Methods Thirteen cases of cerebral embolisms occurred, then accumulated blood pressure, concentrations of serum glucose, lipids, CREA and CsA or FK506, before and after kidney transplantation at the first, second, third month. All these data were analysed. Results Concentrations of serum glucose and lipids were increased significantly after tranplantation （ P 〈 0.05 ）. Prevalence rate of cerebral embolism was higher in kidney transplantation recipients than normal, and to those unnormal serum creastine the rate was also increased（ P 〈 0.01 ）. While change of blood pressure after transplantation had no significant change （ P 〉 0. 05 ）. Conclusion The risk factors for cerebral embolism in kidney transplantation recipients were kidney function, concentrations of serum glcose and lipids,CsA FK506 etc There were correlation between concentrations of CsA and serme T - CHOL or TG, glcose.

关 键 词：肾移植 脑梗死 危险因素 

分 类 号：R699[医药卫生—泌尿科学]