中草药体外抗解脲脲原体的药敏研究  

The Research on Medical Sensitivity of Chinese Herbs Against Uu in Vitro

作　　者：陈万平[1] 林平[1] 边保华[1] 金彩云[1] 余素飞[2] 金保富[2] 

机构地区：[1]台州学院医学院,浙江椒江318000 [2]浙江省临海市台州医院,317000

出　　处：《时珍国医国药》2006年第7期1136-1137,共2页Lishizhen Medicine and Materia Medica Research

基　　金：台州学院资助课题(No.05ND32)

摘　　要：目的探讨解脲脲原体（uu）对20味中草药的敏感性。方法用临床分离的Uu为受试菌，采用几何级稀释法测定20味中草药水煎荆的体外最低抑菌浓度（MIC）。结果20味中草药对Uu均有不同程度的抑菌作用。其中黄柏、蒲公英抑菌效果最好，其MIC范围分别为0．97—7．81g／L和0．97～15．62g／L，MIC50均为3．90g／L，MIC90均为7．8lg／L。抑菌效果最差的是马齿苋、牡丹皮、鱼腥草，敏感率为0％。结论具有清热燥湿、祛风杀虫之功效的中草药体外对Uu具有不同程度的抑菌作用。Objective To investigate the sensitivity of 20 kinds of Chinese herbs against Uu. Methods Test - bacteria were isolated from clinical Uu. Minimal inhibitory concentrations （MIC） of 20 kinds of Chinese herbs decoctions were determined using geometric - progression diluting method in vitro. Results 20 kinds of tested Chinese herbs had bacteriostatic activities against Uu at different extent, among which Cortex Phel/odendr/and Herba Taraxaci were highly active against Uu. Their MIC were 0.97 - 7.81 g/L and 0.97 - 15.62 g/L, MICsowere both 3.90, MIC90were both 7.81. Herba Portulacae, Cortex Moutan Raclicis and Herba Houttuyniae acquired the worst bacteriostatic action, whose sensitivity rates were 0%. Conclusion Chinese herbs which can clear away heat ,dry dampness and expell wind and parasites had bacteriostatic effect against Uu in vitro at different extent.

关 键 词：中草药 解脲脲原体 体外抑菌作用 

分 类 号：R285.5[医药卫生—中药学]