紫外分光光度法测定复方达克罗宁乳膏中盐酸达克罗宁的含量  

Determination of hydrochloride dyclonine from compound dyclonine cream by UV-spectrophotometry

作　　者：谢黎崖[1] 王红梅[2] 邱涵[2] 

机构地区：[1]福建医科大学附属厦门第一医院,厦门361003 [2]厦门市药品检验所,厦门361012

出　　处：《实用药物与临床》2006年第4期205-206,共2页Practical Pharmacy and Clinical Remedies

摘　　要：目的研究应用紫外分光光度法测定复方达克罗宁乳膏中盐酸达克罗宁含量的可行性。方法采用紫外分光光度法。结果盐酸达克罗宁在279nm波长处有最大吸收，在2．5～25μg／mL浓度范围内呈良好线性关系，A=0．0583C＋0．0055，r=1．000；平均回收率为98．20％，RSD=0．5％（n=5）。结论该方法操作简便、结果准确、重现性好，可作为医院制荆质量控制。Objective To develop a method for the determination of hydrochloride dyclonine from compound dyclonine cream. Methods UV-spectrophotometry was used. Results It was absorbed max at 279 nm wavelength. There was a good linear ranged over 2.5- 25 μg/mL of hydrochloride dyclonine, A = 0. 058 3 C ＋ 0. 005 5, r = 1. 000, the recovery was 98.2 % with RS.D = 0.5 %. Conclusion The method is simple, accurate and reproducible, it can be regarded as the conventional quality control in hospital.

关 键 词：盐酸达克罗宁 紫外分光光度法 含量测定 

分 类 号：R927[医药卫生—药学]