银屑病病人血清骨钙素检测  

STUDY OF SERUM OSTEOCALCIN IN PATIENTS WITH PSORIASIS VULGARIS

作　　者：王继文[1,2,3] 秦士德[1,2,3] 彭永年[1,2,3] 冷秀梅 

机构地区：[1]青岛医学院皮肤病学教研室 [2]中国人民解放军济南军区总医院皮肤科 [3]青岛铁路医院皮肤科 检验科

出　　处：《青岛医学院学报》1996年第2期146-147,共2页Acta Academiae Medicinae Qingdao Universitatis

摘　　要：①目的探讨银屑病病人骨组织代谢的变化。②方法应用放免分析法及ＥＤＴＡ滴定法测定４６例寻常型银屑病及３６例其他轻症皮肤病病人的血清骨钙素（Ｏｃ）、甲状旁腺素（ＰＴＨ）和钙离子（Ｃａ２＋）的含量。③结果银屑病组血清Ｏｃ水平明显高于对照组（ｔ＝３．０２４，Ｐ＜０．０１），血清ＰＴＨ及Ｃａ２＋水平低于对照组（ＰＴＨ：ｔ＝２．４３１，Ｐ＜０．０５；Ｃａ２＋：ｔ＝２．１５３，Ｐ＜０．０５）。④结论银屑病病人的骨组织代谢存在异常。Objective To study the bone metabolism of psoriasis vulgaris patients. Method The serum level of osteocalcin(Oc), parathyroid hormone(PTH) and calcium ion (Ca 2+ ) were determined by radioimmunoassay and EDTA trace in 46 psoriasis vulgaris patients and 36 control subjects. Result In psoriasis patients, the serum Oc level was significantly higher than in the control group( t=3.024,P <0 01), while the serum PTH and Ca 2+ values were much lower group(PTH: t=2.431,P <0 05;Ca 2+ : t=2.135,P <0 05). Conclusion There was abnormal bone metabolism in patients with psoriasis vulgaris.

关 键 词：银屑病 血清 骨钙素 甲状旁腺激素 

分 类 号：R758.63[医药卫生—皮肤病学与性病学]