小儿重症肺炎血小板参数的动态变化分析  

Analysis the Dynamic Changes of Platelet Parameters in Children with Severe Pneumonia

作　　者：黄小霏[1] 陈昭仪[1] 范联[1] 

机构地区：[1]广东省佛山市妇幼保健院,528000

出　　处：《岭南急诊医学杂志》2006年第4期269-270,共2页Lingnan Journal of Emergency Medicine

摘　　要：目的:探讨重症肺炎患儿血小板参数动态变化。方法:动态测定38例重症肺炎患儿(A组)的血小板参数包括血小板计数(PLT)、血小板分布宽度(PDW)、平均血小板容积(MPV)及大血小板比率(P-LCR),同时与普通肺炎患儿80例(B组)和正常儿童(C组)100例作对照。结果:入院24h内A组PLT明显高于B、C组,均P<0.01,而PDM、MPV、P-LCR低于C组,差异有显著性,P<0.05;B组PLT高于C组,P<0.05,而PDW、MPV、P-LCR与C组比较无差异,P>0.05。入院72h后复查,B组各血小板参数基本恢复正常,与C组比较无差异,P>0.05;A组PLT明显下降,而PDM、MPV、P-LCR明显升高,与C组比较有显著性差异,P<0.05;入院第7d复查,各参数基本恢复正常。结论:动态检测肺炎患儿的血小板参数有助于准确评估病情的危重度。Objective： To investigate the dynamic changes of platelet parameters in children with severe pneumonia. Methods： Dynamic changes of platelet eount（PLT）,platelet distribution width（PDW）,mean platelet volume（MPV）and platelet-large cell ratio （P-LCR） were detected in 38 children with severe pneumonia （group A）, 80 with general pneumonia（group B） and 100 healthy controls（group C）. Results： PLT in group A was significantly higher than group B and group C,P 〈 0.01, while PDW,MPV.P-LCR were significantly lower than group C in 24 houm,P 〈 0.05. PLT in group B was significantly higher than group C,P 〈 0.05, but PDW.MPV,P-LCR were no differences between group B and C,P 〉 0.05. After 72 hours, the parameters of platelet in group B were recovered. PLT in group A was significantly decreased but PDW.MPV.P-LCR were significantly increased on day 3 and all the parameters of plate.let in group A become normalized on day 7. Conclusions： Simultaneous detection of platelet parameters is helpful in evaluating the severity of pneumonia.

关 键 词：肺炎 血小板参数 小儿 

分 类 号：R725.6[医药卫生—儿科]