子痫前期型肾病综合征79例临床分析  

Clinical analysis of 79 cases of nephrotic syndrome during pregnancy

作　　者：李庆丰[1] 陈敦金 张建平[3] 尹玉竹[4] 张玉洁[5] 

机构地区：[1]广东省广州市红十字会医院,510220 [2]广东省广州市第二人民医院 [3]中山医科大学孙逸仙纪念医院 [4]中山医科大学附属三院 [5]广东省广州市第一人民医院

出　　处：《中国妇幼保健》2006年第14期1920-1921,共2页Maternal and Child Health Care of China

摘　　要：目的:探讨子痫前期型肾病综合征的临床特点及对母婴的影响。方法:回顾性分析广州市五所医院4年79例子痫前期型肾病综合征(肾病组)和160例重度子痫前期病例。结果:子痫前期型肾病综合征占分娩总数的0.19%,占重度子痫前期14.01%。肾病组发病孕周早,24 h尿蛋白、血浆白蛋白、腹水、肾功能受损、早产、小于胎龄儿、新生儿并发症与对照组之间均有非常显著性差异(P<0.01)。两组之间的最高收缩压、最高舒张压和病程无显著性差异(P>0.05)。肾病组围产儿死亡率高于对照组,差异有显著性(P<0.05)。结论:子痫前期型肾病综合征发病孕周早,母婴预后差,适时终止妊娠可减少妊娠期并发症及围产儿发病率和死亡率。Objective： To study the clinical feature and the effect of nephritic syndrome during pregnancy （NSP） to mother and infant. Methods： 79 cases of NSP （NSP group） and 160 cases of severe preeclampsia hypertension （control group） in the past 4 years were reviewed. Results： The NSP was 0. 19% in total deliveries, and account for 14. 01% of severe preeclampsia. The gestation week in which the syndrome diagnosed was earlier in NSP group than in control group. NSP was more likely to have heavier proteinuria, lower plasma albumin level, complicating ascites, renal insufficiency, premature labor, small -for- gestational -age infants and the neonatal complication （P 〈0. 01 ） . However, the blood pressure level and the suffering duration were not significantly different in the two groups （P 〉0. 05 ） . The perinatal mortality was higher in NSP group than in control group （P 〈0. 05） . Conclusion： NSP often occurs early in gestation. The perinatal maternal and fetal prognosis is poor. Early diagnosis and timely termination of pregnancy may improve the outcome.

关 键 词：子痫前期 肾病综合征 临床特点 预后 

分 类 号：R714[医药卫生—妇产科学] R692[医药卫生—临床医学]