液基细胞学联合阴道镜检查在筛查宫颈病变中的作用  

The efficiency of thinprep cell test (TCT) combined with biopsy under colposcopy in diagnosis of cervical squamous intraepithelial lesions.

作　　者：丘惠娜[1] 

机构地区：[1]深圳市第二人民医院妇产科,广东深圳518035

出　　处：《临床和实验医学杂志》2006年第8期1097-1098,共2页Journal of Clinical and Experimental Medicine

摘　　要：目的探讨液基细胞学(TCT)联合阴道镜下组织病理学检查对宫颈病变的筛查价值。方法选择妇科门诊519例临床可疑患者进行宫颈病变筛查,其中268例妇女做TCT检查联合阴道镜活检(实验组),251例直接阴道镜检查活检(对照组),最终均以组织学诊断为金标准,比较两组组织学诊断阳性符合率。结果实验组组织学诊断阳性符合率为72.0%(193/268);对照组为50.1%(126/251)。两组诊断符合率比较差异有高度显著性(χ2=388.62;P<0.005)。结论TCT联合阴道镜检查对宫颈病变的诊断符合率明显高于单一阴道镜检查。Objictive To investigate the effectiveness of thinprep cell test （TCT） combined with biopsy under colpoacope for diagnosis of cervical squamous intraepithelial lesions（CIN）. Methods Five hundred and nineteen suspicious patients were randomly assigned to receive TCT combined with biopsy under colposcope （TCT group, 268 patients） or biopsy under colposcope（ control group, 251 patients）. Pathologic examination of biopsy sample was used as gold standard. Results he agreement on diagnosis of cervical lesions between TCT group and pathologic examination of biopsy sample was 72.0% （ 193/268）, The agreement on diagnosis of cervical lesions between control group and pathologic examination of biopsy sample was 50.1% （ 126/251 ）, the difference was significant（X^2 = 388.62, P 〈 0.005 ）. Conclusion TCT combined with biopsy under colpoacope can significantly improve the diagnostic accuracy of CIN.

关 键 词：液基细胞学 阴道镜 组织学 宫颈病变 筛查 

分 类 号：R711.7[医药卫生—妇产科学]