回声跟踪技术评价家族性高胆固醇血症患者颈动脉弹性的临床研究  

A clinical study on quantitative evaluation of carotid elasticity in familial hypercholesterolemia by echo tracking technique

作　　者：勇强[1] 李治安[1] 蔺洁[2] 王绿娅[2] 

机构地区：[1]首都医科大学附属北京安贞医院超声诊断科,北京100029 [2]首都医科大学心肺血管疾病研究所动脉硬化研究室,北京100029

出　　处：《中华超声影像学杂志》2006年第7期498-500,共3页Chinese Journal of Ultrasonography

基　　金：北京市自然科学基金(7032012);首都医科大学基础临床合作基金(02JL19);北京市科技新星计划(2004B27)

摘　　要：目的应用回声跟踪技术(ET)定量评价家族性高胆固醇血症(FH)患者颈动脉弹性。方法研究对象为7名家族性高胆固醇血症患者及7名正常者,应用血管回声跟踪技术检测双侧颈动脉的弹性系数(Ep)、僵硬度(β)及顺应性(AC)。结果FH患者的Ep、β和AC高于正常对照者,两组的双侧颈总动脉β值、右侧颈总动脉Ep值和左侧颈总动脉AC值差异有统计学意义。结论回声跟踪技术可以作为一种明确FH患者动脉粥样硬化进程的无创伤性血管超声检查新技术。Objective With a newly developed ultrasound-based technique named as echo tracking, to determine the carotid stiffness and compliance in familial hypercholesterolemia（FH） patients. Methods The study population included 8 FH patients with 3 male and 4 female at a mean age of （17.22 ± 5.69） years and 7 normal controls. With the echo tracking technique, the quantitative parameters of Ep, β and the arterial compliance（AC） were detected. Results Ep,β and AC of the subtotal FH patients were higher than that of controls, the statistical significance was found in β of both common carotid arteries, Ep of right common artery and AC of left artery in two groups. Conclusions The echo tracking technique may be a promising modality for noninvasive estimation of the atherosclerotic proceeding in FH patients.

关 键 词：超声检查 颈动脉 高胆固醇血症 家族性 

分 类 号：R589.2[医药卫生—内分泌] R544.1[医药卫生—内科学]