脂肪抑制FSPGR序列:胰腺病变定量和定性分析的ROC曲线评价  

The Evaluation of ROC Curve in Qualitative and Quantitative Analysis of Pancreatic Diseases on Fat Saturation FSPGR Sequence

作　　者：曾庆师[1] 李传福[1] 孟祥水[1] 崔谊[1] 张训河[1] 

机构地区：[1]山东大学齐鲁医院影像中心,山东济南250012

出　　处：《实用放射学杂志》2006年第7期825-828,共4页Journal of Practical Radiology

摘　　要：目的利用ROC曲线评价平扫脂肪抑制FSPGR序列检出胰腺疾病的准确性。方法对92例研究对象行脂肪抑制FSPGR序列扫描,其中57例正常胰腺,35例异常胰腺,测量RO I的信号强度,并计算胰腺相对于肝脏、脾脏的信号强度比值,然后进行定性评价。结果相对于肝脏或者脾脏的信号强度,正常和异常胰腺之间的相对信号强度存在差异。并且胰腺相对于肝脏、脾脏ROC曲线下的面积分别为0.92±0.03、0.91±0.04。与肝脏相比较,对胰腺的定量与定性评价无显著性差异,定性分析检出胰腺病变的敏感性为86.7%,特异性为91.2%。结论在鉴别正常和异常胰腺方面,定性判断与定量分析一样精确,且两者均能够检出胰腺的病变。Objective To evaluate the accuracy of fat - suppressed fast spoiled gradient echo （ FSPGR ） T1 WI in detection of pancreatic disease using the receiver operating characteristic curve （ ROC ） . Methods The pancreas were evaluated in 9 2 subject investigated （ 5 7 normal and 35 with pancreatic disease） with fat saturation FSPGR T1 WI. The signal intensity （ SI） ratio of pancreas relative to liver and spleen was quantitatively measured using regions of interest （ ROIs） , then qualitatively assessed by one independent observers. Results The mean values of pancreas - liver ratios and pancreas - spleen ratios between a normal and an abnormal pancreas were significandy different . Thearea under ROC curve of the pancreas - liver SI ratio and the pancreas - spleen SI ratio was 0.92 ± 0.03 and 0.91 ± 0.04 , respectively . There was no statistically significant difference between quantitative and qualitative analysis for the diagnosis of pancreatic disease when using liver as comparable standard . The sensitivity of qualitative pancreas in comparison with liver was 86.7% , while specificity was 91.2% . Conclusion When the SI ratio of pancreas - liver is used to distinguish normal from abnormal pancreas, qualitative analysis by observers is as accuracy as quantitative

关 键 词：磁共振成像 脉冲序列 胰腺 信号强度 

分 类 号：R445.2[医药卫生—影像医学与核医学] R576[医药卫生—诊断学]