槐白皮抗炎镇痛药理作用的研究  

Studies on the Analgesic and Antiinflammatory Effects of Japanese Pagoda(Sophora japonica)in Mice and Rats

作　　者：刘善庭[1] 李建美[1] 王传功[1] 司端运[1] 李秀英[1] 凌秀珍[1] 

机构地区：[1]济宁医学院,272113

出　　处：《中草药》1996年第12期731-733,共3页Chinese Traditional and Herbal Drugs

摘　　要：槐白皮水提物具有抗炎镇痛作用。能有效的拮抗组胺、二甲苯、醋酸引起的大鼠足趾肿、小鼠耳肿和小鼠腹腔炎性渗出。亦能明显延长钾离子透入刺激引起的大鼠甩尾时间和热板法所致小鼠舔后肢时间。较长时间用药还有增加小鼠胸腺、脾脏重量的作用。Aqueous extract of Huaibaipi (Sophorae japonica)was shown to possess analgesic and antiinflammatory effects. It reduced rat paw edema,mice ear-swelling,and mice inflammatory peritoneal exudatinn induced by histamine, xylene,and acetic acid. It also prolong the tail-twisting time in rats stimulated by potassium ion permeation,and lengthened the leg-licking time in mice provoked by hotplate. Prolong administration can increase the weights of thymus and spleen in mice.

关 键 词：槐白皮 水提物 抗炎 镇痛 中药药理学 

分 类 号：R285.5[医药卫生—中药学]