老年患者呼吸系统真菌感染的检测及临床研究  

Determination and clinical research of respiratory fungal infection in senile patients

作　　者：杨艳秋[1] 贺丹[1] 许建成[2] 张云峰[2] 张波[2] 横山耕治[3] 王丽[1] 

机构地区：[1]吉林大学基础医学院病原生物学教研室,吉林长春130021 [2]吉林大学第一医院 [3]日本国立千叶大学真菌医学研究中心

出　　处：《中国老年学杂志》2006年第7期930-932,共3页Chinese Journal of Gerontology

基　　金：国家自然科学基金资助项目(30571773);吉林省科技发展计划重点资助项目(20050205-3)

摘　　要：目的探讨老年患者肺部真菌感染的危险因素和流行病学特征,为控制真菌感染提供依据。方法根据真菌形态学及生化学特征,进行真菌的鉴定;调查医院真菌感染的流行病学特征;对67例医院真菌感染进行回顾性统计分析。结果从72份疑似真菌感染患者的痰液标本中,分离得到真菌67株,检出率为93.1%。其中,白色念珠菌感染率最高(53.73%),其次为光滑念珠菌(14.94%)、热带念珠菌(7.46%)、克柔念珠菌(7.46%),构成比与以往报道有差异;除念珠菌属外,还分离到曲霉属(13.43%)等真菌。结论老年患者肺部真菌感染发生率较高,正确地进行菌种的鉴定,对临床真菌感染的诊断及治疗具有重要意义。Objective To investigate the risk factors, epidemiological feature of pulmonary fungal infection and provide evidence for controlling infection in senile patients. Methods According to fungal morphology and biochemical character, pathogenic fungi were identified to investigate the epidemiological feature of nosecomial fungal infection. The clinical data of the 67 senile patients with pulmonary fungal infection were retrospectively analyzed. Results Among 67 stains isolated from 72 specimen （93.1% ）, there was Candida albicans （53.73 % ） followed by Candida glabrata （ 14. 94% ）, Candida tropicalis （7.46%）, Candida krusei （7.46%） and Aspergillus （ 13.43% ）. Conelusions The morbidity of senile patients with pulmonary fungal infection was very high. It is necessary to make efforts to control the risk factors to reduce the morbidity.

关 键 词：真菌感染 呼吸道 分离 鉴定 

分 类 号：R379[医药卫生—病原生物学] R563.1[医药卫生—基础医学]