介入治疗继发孔房间隔缺损及合并畸形428例临床报告  

Transcatheter devices closure of secundum atrial septal defects complicated with other malformations in 428 patients

作　　者：邓东安[1] 朱鲜阳[1] 侯传举[1] 韩秀敏[1] 

机构地区：[1]沈阳军区总医院心研所先心内科,辽宁沈阳110016

出　　处：《中国介入影像与治疗学》2006年第4期255-258,共4页Chinese Journal of Interventional Imaging and Therapy

摘　　要：目的探讨继发孔房间隔缺损(ASD)合并畸形的介入治疗适应证、操作原则及临床效果。方法继发孔型ASD住院患者428例,其中单一ASD 416例,多发型ASD 12例,合并畸形70例。介入术中导入球囊导管测量最大ASD伸展直径,用TTE或TEE测量ASD直径及确定ASD位置、大小及数目。用注入球囊中的混合造影剂抽出在体外卡尺测量ASD直径,据此选择合适的闭合器。结果428例ASD患者成功介入425例,介入技术成功率99.3%。介入手术并发症总发生率2.1%。本组合并畸形介入治疗成功率100%。结论ASD及合并畸形的介入治疗,主要掌握ASD及合并畸形疾病的适应证,操作规范化,成功率很高,而且安全有效。Objective To evaluate indications, technical procedurals and clinical efficacy of transcatheter closure of secundum atrial septal defects （ASD） complicated with other malformations. Methods All of 428 consecutive patients with secundum ASD was included in the study. All ASD patients were central, including single ASD （n=416） and multiple ASD （n=12）. In addition, 70 patients accompanied other malformations. The maximum diameter of the ASD was measured by the stretched balloon diameter, position and number was decided by transesophageal echocardiography or transthoracic echocardiography. Device size was selected by adding 2 to 4 mm to the largest ASD diameter. Results Devices were successfully implanted into 425 （99.3%） of 428 patients. Total complications rate was 2.1%. In this group, all of malformations were successfully cured （100%）. Conclusion This single-center experience with percutaneous device closure of ASD demonstrates excellent results with few early and late complications.

关 键 词：房间隔缺损 畸形 并发症 超声心动图 介入治疗 

分 类 号：R541.1[医药卫生—心血管疾病] R540.45[医药卫生—内科学]