中国6城市中老年人群颈椎骨关节炎患病危险因素的非条件Logistic回归分析(英文)  

Non-conditional Logistic regression analysis on risk factors of cervical osteoarthritis in the middle-aged and elderly from 6 cities of China

作　　者：李宁华[1] 薛庆云[1] 王坤正[2] 李恩[3] 朱汉民4 金大地5 陶天遵6 裴福兴7 

机构地区：[1]卫生部北京医院,北京市100730 [2]西安交通大学第二医院骨科,陕西省西安市710004 [3]河北医科大学中西医结合研究所,河北省石家庄市050017 [4]上海华东医院,上海市200040 [5]广州南方医院脊柱骨病外科,广东省广州市510515 [6]哈尔滨医科大学第二附属医院骨外二科,黑龙江省哈尔滨市150086 [7]四川大学华西医院骨科,四川省成都市610041

出　　处：《中国临床康复》2006年第32期160-162,共3页Chinese Journal of Clinical Rehabilitation

基　　金：国家"十五"科技攻关计划资助项目(2004BA702B06)~~

摘　　要：背景:中老年人的颈椎骨关节炎发病率较高,国外对引起颈椎骨关节炎的危险因素已进行了一些研究,但大多数因素尚在讨论之中。目的:调查国内不同地区间中老年人群颈椎骨关节炎的患病危险因素,为颈椎骨关节炎的社区预防干预提供依据。设计:横断面调查。单位:卫生部北京医院联合西安交通大学第二医院、河北医科大学中西医结合研究所、上海华东医院、南方医院、哈尔滨医科大学第二附属医院、四川大学华西医院共同完成。对象:调查于2005-07/08完成。采用分层多阶段整群抽样方法,选择西安、石家庄、上海、广州、哈尔滨市及成都6城市40岁及以上具有正式户口的常住居民6218人,均自愿参加调查。其中男2916人,女3302人,年龄男性40～94岁,女性40～86岁。方法:对调查人群进行颈椎骨关节炎的流行病学问卷调查,对有临床症状者行X射线摄片。本次调查的基本抽样单位是居委会(城市)和村委会(农村)。抽样方法以各城市为总体,分为城市和农村两层,第一阶段抽取区(县),第二阶段抽取街道(乡),第三阶段抽取居委会(村委会)。颈椎骨关节炎诊断标准为颈椎骨关节炎临床症状阳性加X射线Kell-gren&Lawrence分级2级及以上。问卷调查内容包括6个方面:包括一般情况、现病史、既往史、体格检查、X射线片检查情况及疾病诊断情况,共计94个问题141个变量指标。分析颈椎骨关节炎患病率的影响因素应用多因素非条件Logistic回归法,表示疾病与暴露因素之间联系强度的指标用比值比(OR),若OR>1,说明疾病发生与暴露因素呈正关联;若OR<1,说明疾病发生与暴露因素呈负关联。主要观察指标:各城市颈椎骨关节炎的患病率和OR。结果:纳入调查对象6218人,全部进入结果分析,无脱落。①国内6城市40岁及以上人群颈椎骨关节炎总患病率为23.6%,各城市患病率相比差异有显著性意义(P<0.01BACKGROUND： Incidence rate of cervical osteoarthritis in the middleaged and elderly is high. Some researches on risk factor causing cervical osteoarthritis have been performed abroad, but most of the factors are being discussed. OBJECTIVE： To investigate the occurring cervical osteoarthritis risk factors in the middle-aged and elderly from different regions of China and provide evidences for prevention and intervention of cervical osteoarthritis in community. DESIGN： Cross-sectional study. SETTING： Beijing Hospital, Ministry of Health, together with Second Hospital of Xi＇an Jiantong University, Institute of Integrated Traditional and Western Medicine of Hebei Medical University, Shanghai Huadong Hospital, Nanfang Hospital, Second Affiliated Hospital of Harbin Medical University, West China Hospital of Sichuan University. PARTICIPANTS： The investigation was conducted from July to August 2005. On the basis of stratified multi-stage cluster sampling method, 6 218 formal registered permanent residents of over 40 years old from Xi＇an, Shijiazhuang, Shanghai, Guangzhou, Harbin and Chengdu were enrolled. They all agreed to join the investigation voluntarily. There were 2 916 males of 40-94 years and 3 302 females of 40-86 years. METHODS： Questionnaire investigation of epidemiology of cervical osteoarthritis was performed in the testees, and radiograph was used in the persons with clinical symptom. The basic sample unit was neighborhood committee （city） and village committee （countryside）. Sampling method： Taking each city as a whole, composed of two levels, namely city and countryside, in the first phase the persons were extracted from district （county）, in the second phase from sub-district （countryside）, in the third phase from neighborhood committee （village committee）. Diagnosis standard of cervical osteoarthritis was positive clinical symptom and 2 grade or above of radiograph Kellgren ＆ Lawrence grading. The content of questionnaire contained 6 aspects： general c

关 键 词：骨关节炎 颈椎病 因素分析 抽样研究 

分 类 号：R684.3[医药卫生—骨科学]