国产电解可脱性铂弹簧圈栓塞颅内动脉瘤的临床应用  

Endovascular embolization of intracranial aneurysms with electrolytically detachable coils made in China:a clinical application

作　　者：尹龙[1] 焦德让[1] 孙瑞发[1] 武秀生[1] 李旭东[1] 康伟民[1] 黄楹[1] 

机构地区：[1]环湖医院神经外科,天津300060

出　　处：《中国脑血管病杂志》2006年第7期297-302,共6页Chinese Journal of Cerebrovascular Diseases

摘　　要：目的比较天津环湖医疗器械厂研制生产的电解可脱性铂弹簧圈（sunruifa electrical detachable coil，SEDC）和美国Micro Therapeutics，Inc公司生产的电解可脱性铂弹簧圈（sapphire detachable coil，SDC）栓塞颅内动脉瘤的临床应用情况。方法颅内动脉瘤患者91例，30例使用SEDC行颅内动脉瘤栓塞（SEDC组）；61例采用SDC栓塞（SDC组）。两组患者在同一时间段．由同一术者使用同种微导管进行治疗。术中观察两种弹簧圈在X线下的可视性、在推送中的顺滑程度、解旋情况、软硬程度、成篮效果、致密填塞情况及解脱时间。采用电话、门诊及数字减影血管造影进行随访。结果SEDC组共用SEDC 108枚，SDC组用SDC 271枚。在X线透视下SEDC与SDC同样清晰可见，在微导管中推送弹簧圈时，SEDC组有2枚欠顺滑，SDC组有9枚欠顺滑；在反复推拉弹簧圈时，SEDC组有5枚发生解旋，SDC组有8枚解旋；SEDC组电解脱时间有6枚超过5min，SDC组有10枚超过5min。经统计学分析，各项观察指标两组比较差异无显著性。SEDC组动脉瘤致密填塞25例，SDC组49例，SEDC组瘤颈残留2例，SDC组5例，SEDC组非致密填塞3例，SDC组7例，两组比较差异无显著性。两组均随访3～22个月，无再出血，两组中各有2例术后获得DSA随访，均未见动脉瘤复发。结论SEDC可以替代SDC栓塞颅内动脉瘤。Objective To compare Sunruifa electrolytically detachable coil （ SEDC ; developed and produced by Huanhu Medical Apparatus and Instrument, Inc. , Tianjin, China） with Sapphire detachable coil （SDC; produced by Micro Therapeutics, Inc, USA） in embolization of intracranial aneurysms in clinical application. Methods Of the 91 patients with intracranial aneurysms, 30 were treated with SEDC （SEDC group）, and 61 were treated with SDC （SDC group） for the embolization of intracranial aneurysms. Both groups were treated at the same time period, by the same surgeon, and with the same type of microcatheter. The visibility of both coils, easiness of deployment through microcatheter, uncoiling, flexibility, effect of forming a basket, dense packing, and time needed for detachment were observed under the fluoroscopy during the procedures. The patients were followed up by telephone, outpatient appointment and digital subtraction angiography. Results A total of 108 and 271 coils were used in the SEDC group and SDC group, respectively. Both kinds of coils could be clearly visible under the fluoroscopy. Friction was observed when 2 of the coils in the SEDC group and 9 in the SDC group were pushed through the microcath- eter. Five coils in the SEDC group and 8 in the SDC group were stretched during the repositioning. Electrolytically detaching time of 6 coils was more than 5 minutes in the SEDC group and 10 in the SDC group. All the outcome measures in both groups were not statistically significant. The densely packed aneurysms were 25 patients in the SEDC group, and 49 in the SDC group; neck remnant in the SEDC group and SDC group was 2 and 5 patients, respectively; the loosely packed aneurysms were 3 patients in the SEDC group, and 7 in the SDC group. There was no significant difference between the two groups. Both groups were followed up for 3 to 22 months, and no rebleeding occurred. Two patients in each group were followed up with DSA, and no recurrence of aneurysm was observed. Conclusion SEDC can replace SDC

关 键 词：颅内动脉瘤 治疗 栓塞性 电解可脱性弹簧圈 

分 类 号：R651.12[医药卫生—外科学]