大豆异黄酮软胶囊治疗黄褐斑与抗氧化能力的实验研究  

The experimental study of the soybean isoflavones soft cupsule on the removing chloasmas and the ablity of antioxidation

作　　者：金道山[1] 梅世昌[1] 王锦传[2] 

机构地区：[1]解放军总医院科技成果转化中心 [2]解放军总医院科技成果转化中心1北京100853

出　　处：《中国美容医学》2006年第7期834-835,共2页Chinese Journal of Aesthetic Medicine

摘　　要：目的:观察大豆异黄酮软胶囊治疗黄褐斑与其抗氧化能力间的关系。方法:采用老年雌性大鼠为实验动物模型,每天灌服大豆异黄酮软胶囊内容物,连续90天,检测服药后大鼠血及肝组织中超氧化物歧化酶(SOD)、谷胱甘肽过氧化物酶(GSH-PX)活性及脂质过氧化物(MDA)含量。结论:大豆异黄酮软胶囊提高大鼠血及肝组织中SOD、GSH-PX活性(P<0.05,P<0.01),降低血及肝组织中MDA含量(P<0.05,P<0.01)。结论:大豆异黄酮软胶囊治疗黄褐斑与其抗氧化能力间有密切关系。Objective To observe the relation of the removing chloasmas and the ablity of antioxidation in the soybean isoflavones soft cupsule.Methods To used old female rat for experoiental animal model,to pour stomach the soybean iaoflavones soft capsule every day for 90 days, to determine the activity of superoxide dismatase（SOD） and glutathion peroxidase （GSH-PX）, and the contenet of malodehydic acid （MDA） in rat blood and liver tissue. Results The soybean isoflavones soft capsule raise the activity of SOD and GSH-PX（P〈0.05,P〈0.01）, and reduce the content of MDA（P〈0.05,P〈0.01）in rat blood and liver tissue, Conclusion It has the closer relation between the removing chloasmas and antioxidation in the soybean isoflavones soft capsule.

关 键 词：大豆异黄酮 软胶囊 黄褐斑 

分 类 号：R246[医药卫生—针灸推拿学]