女童性早熟113例临床分析  

Clinical analysis on 113 girls with precocious puberty.

作　　者：尹方[1] 王刚[1] 仇永[1] 

机构地区：[1]广东佛山市第一人民医院,佛山528000

出　　处：《中华妇幼临床医学杂志（电子版）》2006年第4期210-212,共3页Chinese Journal of Obstetrics & Gynecology and Pediatrics(Electronic Edition)

摘　　要：目的探讨女性儿童性早熟的临床特征。方法对113例女性儿童性早熟病例的临床分类、骨龄、致病原因等进行回顾性分析。结果113例女性儿童性早熟病例中,中枢性性早熟(CPP)43例(38.1%),外周性性早熟(PPP)70例(61.9%)。CPP患儿促性腺激素释放激素(GnRH)激发试验呈阳性,骨龄比生理年龄明显升高至少1年以上;PPP患儿GnRH激发试验呈阴性,骨龄与生理年龄基本相符。饮食情况调查显示,PPP组患儿中,经常食用饮料、肉禽、水产及补品的比例明显高于CPP组。结论女童性早熟在诊断和鉴别诊断上比较复杂,常需综合分析。部分PPP女童可在无任何征兆的情况下转变为CPP,应引起高度重视,食品性激素污染,尤其值得食品生产监督部门的高度关注。Objective To analysis the clinical characteristics of girls with precocious puberty. Methods 113 cases with precocious puberty were reviewed restrospectively. Results 43 cases were CPP （38. 1 %）, 70 cases were PPP（61.9%）. GnRH stimulation test of each case in CPP group was positive, bone age advancement was more than chronological age at least 1 year. GnRH stimulation test of each case in PPP group was negative, bone age was the same with chronological age. The investigation of dietetic habit of these cases showed： most of PPP cases were addicated to meat. Conclusion The diagnosis of girl＇s precocious puberty is very complicated. Some of PPP cases could transform to CPP without any sign. Food pollution should he given enough attention by government.

关 键 词：性早熟 女性儿童 骨龄 

分 类 号：R725.8[医药卫生—儿科]