急性失血对心脏功能的动态模拟  

Numerical Simulation of Cardiac Function in Response to Acute Hemorrhage

作　　者：周希平[1] 王国卿[1] 邹容[1] 

机构地区：[1]苏州大学医学院基础医学系,江苏苏州215123

出　　处：《中国血液流变学杂志》2006年第2期194-196,共3页Chinese Journal of Hemorheology

基　　金：苏州大学医学发展基金(EE134521)

摘　　要：目的在急性失血条件下,用计算机仿真方法评价心脏功能的变化。方法利用包含多种心血管反射的血流动力学模型,采用ODE45可变步长算法模拟急性失血。结果失血后主动脉压力、输出量和每搏输出量均减少。在血容量减少时, 静脉非压力容积与血管阻力相比,对重建稳态起了更重要的调控作用。结论仿真模型可以作为动物实验的预研手段。Objective A mathematical model for simulation of acute hemorrhage were developed to simulate the properties of cardiac function.Method The model is built on Matlab/Simulink system with ODE45 algorithm. Results The simulation experiments show that venous unstressed volume plays an important part in controlling of hemorrhage.Conclusion The model is easy to extend,it can be used as an assistant tool for animal experiment.

关 键 词：急性失血 颈动脉窦反射:数字仿真 

分 类 号：R331.3[医药卫生—人体生理学]