觉醒在儿童阻塞性睡眠呼吸暂停低通气综合征中的变化与意义  

Arousal response in child patients in obstructive sleep apnea

作　　者：王卫之[1] 王欣[1] 王岩[1] 王廷础[1] 

机构地区：[1]山东大学卫生部耳鼻咽喉科学重点实验室,济南250012

出　　处：《临床耳鼻咽喉科杂志》2006年第15期691-693,共3页Journal of Clinical Otorhinolaryngology

摘　　要：目的:探讨觉醒在儿童阻塞性睡眠呼吸暂停低通气综合征(OSAHS)中的变化与意义。方法:采用32导PSG监测仪,Polysmith睡眠分析软件,按国际通用标准导联连接方法,对48例睡眠呼吸障碍儿童进行整夜监测。按国际通用标准,对比分析OSAHS患儿(OSAHS组)与单纯打鼾儿童(单纯打鼾组)的觉醒变化。结果:OSAHS组的学龄前亚组和学龄期亚组非快速眼动期(NREM)1、2、3期加4期和快速眼动期(REM)几项指标,分别与单纯打鼾组的学龄前亚组和学龄期亚组比较,差异均无统计学意义(均P>0.05);而伴AHI觉醒指数(ArI)、伴腿动(LM)的ArI和总ArI指数OSAHS组的学龄前亚组均明显高于单纯打鼾组的学龄前亚组(均P<0.05);而伴鼾声ArI、自发性ArI分别与单纯打鼾组的学龄前亚组和学龄期亚组比较,差异均无统计学意义(均P>0.05)。结论:OSAHS组患儿的睡眠为不安定睡眠,这种睡眠虽未造成睡眠结构的改变,但引起伴AHI的ArI、伴LM的ArI与总ArI数量的增加。Objective： To analyze arousal response of Polysomnography（PSG） in children with obstructive sleep apnea-hypopnea syndrome （OSAHS）. Method： Fourty-eight children with sleep disorder were studied with 32 guide Polysomnography and analyzed by Polysmith. Sleep structure and arousals of preschool-aged and school-aged children with OSAHS were compared with those of primary snore patients. Result：The mean value of AHI of preschool aged children with OSAHS was （10.6±8.9）h, of AI was（ 4.0±7. 1）h ,of HI was （6.6±4.6）h; The sleep structure between OSAHS group and primary snore group was not significant（ P〉0.05）. The mean value of Arl with AHI was（8.2±5.9）h,of ArI with LM was （19.6±5.8）h,whole Arl was 49.3±20.4 in preschoolaged children with OSAHS; The mean value of Arl with AHI was（7.6±6.3）h,of ArI with LM was （14.3±7.6） h,whole Arl was 49.9±14.9 in school-aged children with OSAHS . Those of OSAHS children were higher than that of primary snore patients （ P〈0.05）. Conclusion： Althought OSAHS in children is characterized by a restlesssleep,the structure is prefect and mildly affected by OSAHS. The ArI with AHI, with LM and the whole ArI in OSAHS children is higher than those of primary snore patients.

关 键 词：儿童 睡眠呼吸暂停低通气综合征 阻塞性 觉醒 多导睡眠监测 

分 类 号：R563.8[医药卫生—呼吸系统]