微生态制剂(培菲康)对小儿肺炎继发腹泻的预防作用  

Prevention effect of microecological modulator(Peifeikang) on pneumonic infants with secondary diarrhea

作　　者：林滨榕[1] 唐秋雨[1] 吴斌[1] 

机构地区：[1]福建医科大学附属第一医院,福建福州350005

出　　处：《儿科药学杂志》2006年第4期31-32,53,共3页Journal of Pediatric Pharmacy

摘　　要：目的：探讨预防性应用微生态制剂（培菲康）对小儿肺炎继发腹泻的防治效果。方法：2002年5月-2004年5月住院治疗的肺炎患儿428例随机分为预防组和对照组。预防组在入院后即开始应用微生态制剂，用药时间均在72h以上；对照组入院后始终未用或住院时间72h后因出现继发腹泻才开始应用微生态制剂。结果：预防组210例住院治疗期同继发腹泻病发病率为18．57％（39／210）；对照组218例住院治疗期间继发腹泻病的发病率39．45％（86／218），两组间差异具有统计学意义（0=22．55，P〈0．001）。结论：预防性应用微生态制剂（培菲康）能减低肺炎患儿继发腹泻的发生率。Objective： To study the prevention and treatment effect of microecological modulator （Peifeikang） used in advance on pneumonic infants with secondary diarrhea. Methods： 428 pneumonie infants in hospital from May, 2002 to May, 2004 were randomly divided into defend group and control group. The infants who used mieroeeologieal modulator as soon as after being in hospital with the time of dosing beyond 72 hours were put into the defend group; the infants who never used mieroeeologieal modulator after being in hospital or used mieroeeologieal modulator because of pneumonia with secondary diarrhea after 72 hours in hospital were put into control group. Results： The defend group of 210 eases used Peifeikang to prevent and cure diarrhea, and the ratio of diarrhea during treatment in hospital was 18.57% （39/210） ; while the control group of 218 cases didn＇t use Peifeikang, and the ratio was 39.45% （86/218）. The difference between two groups had statistic signifieance （χ^2= 22.55, P 〈 0.001）, Conclusions： Microecological modulator （Peifeikang） used in advance can decrease the ratio of secondary diarrhea on pneumonia infants.

关 键 词：肺炎 腹泻 微生态制剂 儿童 

分 类 号：R925.7[医药卫生—药学]