阻遏诱变剂镉在海洋生物中传递的物质及作用机理的研究（Ⅱ）维生素E  

STUDY ON THE PROHIBITOR AGAINST TRANSFER OF Cd 2+ -MUTAGEN IN MARINE ORGANISMS AND ITS MECHANISM Ⅱ.VITAMIN E

作　　者：林光恒[1] 刘明星[1] 孙国琼[1] 

机构地区：[1]中国科学院海洋研究所

出　　处：《癌变．畸变．突变》1996年第5期272-276,共5页Carcinogenesis,Teratogenesis & Mutagenesis

基　　金：国家自然科学基金

摘　　要：本文报告了利用维生素Ｅ和中国对虾（Ｐｅｎａｅｕｓｏｒｉｅｎｔａｌｉｓ）为材料，通过给中国对虾喂食添加维生素Ｅ的含镉饵料，并分别以含镉饵料和普通饵料作对照，证明维生素Ｅ可以有效地抑制、阻遏或减少对虾对镉的吸收，从而降低镉在对虾体内潜在的毒害作用。化学分析和紫露草四分体微核分析均证实了维生素Ｅ是一种有效的诱变剂镉的抑制剂，可以用来阻遏诱变剂镉在海洋食物链中的传递，从而减少甚至阻断镉经海洋生物进入人体。Cadmium is a common heavy metal pollutant in marine environment.It exists mainly in sea water and substrata,and has marked toxicity to marine organisms in the stages of larva,juvenile and maturity.Our former works had demonstrated cadmium was an important mutagen in the sea and could be transfered via marine food chains from lower organisms to higher ones and eventually into human bodies after consuming.Present paper reports the experimental results of vitamin E in prawn,Penaeus orientalis and reveals it has a remarkable function of prohibiting and decreasing of Cd 2+ -absorption by the prawn.Therefore,it is possible using vitamin E as a prohibitor against transfer of Cd 2+ -mutagen in marine organisms.This conclusion was verified by both of chemical analysis with PRGP and mutagenic test with Trad-MCN.

关 键 词：维生素E 镉 诱变剂 对虾 海洋生物 

分 类 号：R992[医药卫生—毒理学]