雷米普利联合缬沙坦对慢性心力衰竭患者心脏重构及心功能的影响  

The influence of ramipril in addition to valsartan on heart remdoeling and function in chronic heart failure patients

作　　者：李天东[1] 于华[1] 朱震[1] 

机构地区：[1]青岛大学医学院附属心血管病医院心内科,山东省青岛市266071

出　　处：《中国心血管病研究》2006年第8期582-583,共2页Chinese Journal of Cardiovascular Research

摘　　要：目的观察雷米普利、缬沙坦联合对慢性心力衰竭患者心脏重构及心功能的影响。方法150例慢性心力衰竭患者分为两组,对照组应用雷米普利及常规治疗,治疗组加用缬沙坦,治疗6个月后观察心功能与心脏结构的变化。结果在应用雷米普利的基础上加用缬沙坦可以明显改善左心室射血分数、左心室舒张末期内径和左心室短轴缩短率及心胸比例。结论联合治疗可以改善心脏重构和心功能。Objective To observe the influence of ramipril in addition to valsartan on heart remodeling and function in chronic heart failure patients. Methods Heart structure and function were measured in 150 patients after 6 month treatment of ramipril in addition to valsartan. Results LVDD,LAD,FS,EF,heart thoracic ratio were significantly improved after treatment. Conclusion combination of ramipril,valsartan can improve the remodeling and heart function in chronic heart failure.

关 键 词：心肌血管重建术 雷米普利 缬沙坦 心力衰竭 充血性 药物疗法 

分 类 号：R541.61[医药卫生—心血管疾病]