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作 者:许太武[1,2] 丁玉兴[1,2] 李晓亮[1,2] 张步振 高明[1,2]
机构地区:[1]昆明市成都军区昆明总医院 [2]昆明医学院第一附属医院
出 处:《中国危重病急救医学》1996年第10期604-605,共2页Chinese Critical Care Medicine
摘 要:探讨创伤患者急性期血糖(Glu)含量变化与动脉收缩压(SBP)、血氧饱和度(SaO2)及预后的关系。测定31例创伤患者术前的Glu含量,结合SBP、SaO2进行对比研究。结果:创伤组术前Glu(8.14±2.47mmol/L)与正常组(4.72±1.38mmol/L)比较有极显著性差异(t=6.37,P<0.001);SBP<8.0kPa(1kPa=7.5mmHg)与>8.0kPa组比较,Glu(10.32±2.37mmol/L比6.74±1.32mmol/L)和SaO2(0.74±0.37比0.91±0.11)均有极显著性差异(P均<0.001),并且SBP越低,Glu越高,SaO2呈直线下降;术前Glu与患者的预后也显著相关,死亡组术前Glu(12.53±1.73mmol/L)明显高于存活组(7.35±1.56mmol/L),而SBP(4.29±4.13kPa)、SaO2(0.29±0.06)则明显低于存活组(分别为10.86±1.78kPa和0.88±0.08,P<0.001)。作者结合文献复习就创伤患者高血糖的发生机制。To study the relationship of blood glucose(Glu).with blood pressure,blood oxygen saturation (SaO 2)and the prognosis,the serum Glu,systolic blood pressure(SBP),SaO 2 were measured in 31 patients with trauma.The results showed that Glu was higher in patients with trauma (8 14±2 47mmol/L)than normal subjects(4 72±1 38mmol/L)( t =6 37, P <0 001).There was a significant difference in Glu and SaO 2 between the patients with SBP<8 and >8kPa,and the lower the SBP,the higher the Glu(10 32±2 37mmol/L vs 6 74±1 32mmol/L),with a linear decrease of SaO 2(0 74±0 37 vs 0 91±0 11)( P <0 001).In addition,the preoperative Glu was significantly related to the patients' prognoses.The Glu in the patients of the group of death (12 53±1 73mmol/L)was significantly higher than that of the survivors(7 35±1 56mmol/L),but SBP(4 29±4 13kPa) and SaO 2 (0 29±0 06)were significantly lower(in surviors,SBP 10 86±1 78kPa,SaO 2 0 88±0 08)( P <0 001).The mechanism of hyperglycemia and the influence of hyperglycemia on the prognosis,as well as the treatments were discussed.
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