铜绿假单胞菌β-内酰胺类药物耐药相关基因(12种)研究  

Study on the drug-resistant genes associated β-lactams in Pseudomonas aeruginosa

作　　者：王伟[1] 毛剑锋[1] 陈英[1] 薛武进[1] 

机构地区：[1]丽水市人民医院,浙江丽水323000

出　　处：《中国微生态学杂志》2006年第4期285-287,共3页Chinese Journal of Microecology

摘　　要：目的了解临床分离的铜绿假单胞菌β-内酰胺类药物耐药相关基因(12种)存在状况。方法自临床分离40株对铜绿假单胞菌,采用聚合酶链反应(PCR)检测耐药基因(TEM、SHV、OXA-10群、CTX-M-1群、PER、VEB、GES、CARB、IMP、VIM、DHA和oprD2)。结果40株中CARB阳性18株(45.0%)、35株oprD2基因缺失(87.5%),其余基因均阴性。结论临床分离的铜绿假单胞菌CARB基因携带率高。Objective To investigate the drug-resistant genes associated β-lactams in Pseudomonasaeruginosa isolated Lishui,Zhejiang. Methods 40 strains of Pseudomonas aeruginosa were isolated from hospitalized patients, and drug-resistant genes were detected by PCR. Results The positive rates of genes CARB were all 45.0%, 35 strains oprD2-gene was lack, Genes of TEM, SHV, OXA-10 group, CTX-M-1 group, PER, VEB, GES, IMP, VIM and DHA were not found in all 40 isolated tested. Conclusion There were very high positive percentages of CARB genes

关 键 词：铜绿假单胞菌 Β-内酰胺酶类 耐药基因 

分 类 号：R378.991[医药卫生—病原生物学]