萘酰氨基修饰β-环糊精对几种荧光染料的分子识别  

Molecular Recognition of Several Fluorescent Dyes by β-Cyclodextrins Modified with Naphthyloxamino

作　　者：赵焱[1] 刘哓青[1] 赵勇[1] 刘频[1] 李琮[1] 

机构地区：[1]云南师范大学化学化工学院,昆明650092

出　　处：《分析化学》2006年第7期959-962,共4页Chinese Journal of Analytical Chemistry

基　　金：云南省自然科学基金(No.2003B0014Q);云南省教育厅科研基金(No.03Y313A)资助项目

摘　　要：用光谱滴定技术分别测定了β-环糊精(1)、单-[6-(1-萘酰氨基)-乙基氨基-6-脱氧]-β-环糊精(2)、单-[6-(1-萘酰氨基)-二乙基二氨基-6-脱氧]-β-环糊精(3)在25℃时,pH为7.2、2.0和10.1的缓冲溶液中与几种染料分子形成超分子配合物的稳定常数Ks,并考察了pH=7.2时识别过程的热力学参数ΔH0和TΔS0。结果表明,pH为2.0和10.1时,静电、疏水和氢键作用协同贡献于超分子配合物的形成,如主体2与AR在pH=10.1时形成的Ks=7085;而pH=2.0时的Ks=1034。当pH=7.2时主-客体的尺寸/形状匹配、疏水作用和范德华力决定配合物的稳定性。主体2、3对AR、TNS和ANS的包结配位是放热过程,并给出较大的焓变(-ΔH0),对RhB主要表现为熵驱动过程。The spectral titrafions have been performed to give the stability constants Ks for the supermolecular systems formed by β-cyclodextrin （ 1 ） , mono [ 6-（ 1-naphthyloxamino ） ethylenediamino） -6- dexoy ] -β-cyclo- dextrin（2 ）, mono [ 6-（ 1-naphthyloxamino ） diethylenediamino ） -6-dexoy ] -β-cyclodextrin （ 3 ）, with some dyes in aqueous buffers of pH 7.2, 2.0 and 10. 1 at 25℃. Moreover, the thermodynamic parameters （ AH and TAS ） for the inclusion complexation were also calculated at pH 7.2. The results obtained indicated that electrostatic, hydrophobic and hydrogen bonding interactions cooperatively contributed to the formation of supramolecular complexes at pH 2.0 and pH 10.1 respectively. Typically, host 2 with acridine red （AR） displayed the binding ability （Ks = 7085） at pH 10. 1, but Ks = 1034 at pH 2.0. On the other hand, the size/shape-matching between host and guest, hydrophobic and van der Waals interactions determined the stability of inclusion complex at pH 7.2. The inclusion reactions of 2, 3 with AR, sodium-2-p-methyl phenylamino-6-naphthalene sulfonate （TNS） and ammonium-phenylaminonaphthalene sulfonate （ANS） were exothermic, giving the larger negative enthalpic gain （ - AH ）, but the inclusion complexation with RhB was mainly entropy-driven contribution.

关 键 词：修饰环糊精 染料分子 分子识别 超分子配合物 热力学 

分 类 号：O657.3[理学—分析化学]