气相色谱法测定补骨脂中的有效成分  

Determination of effective compounds in Psoralea corylifolia by GC

作　　者：姚三桃[1] 杨滨[1] 徐植灵[1] 

机构地区：[1]中国中医研究院中药研究所

出　　处：《中国药学杂志》1996年第7期394-396,共3页Chinese Pharmaceutical Journal

基　　金：*为"八五攻关"课题

摘　　要：目的：建立气相色谱法测定补骨脂药材中有效成分的含量。方法：采用３０ｇ／ＬＳＥ３０填充柱，氢火焰离子检测器，以氧化铝柱净化样品，为６，７－二甲氧基香豆素为内标物，内标二点法定量。结果：对国内１１个地区的补骨脂中补骨脂素和异补骨脂素进行测定，含量分别为０．０５％～１．１７％及０．１６％～１．２０％。OBJECTIVE:To establish a GC method to determine the contents of active compounds psoralen and isopsoralen in fructus Psoraleae.METHOD:Stationary phase:3% SE 30 ;FID detector;6,7 dimethoxy coumarin as internal standard.RESULTS:Several samples of 11 areas were analyzed by this method.The content of psoralen ranged from 0.05% to 1.17%.The content of isopsoralen varied from 0.16% to 1.20%.CONCLUSION:This method is a simple and feasible way to control the quality of fructus Psoralea.

关 键 词：补骨脂 补骨脂素 异补骨脂素 气相色谱法 中药 

分 类 号：R284.1[医药卫生—中药学]