768例老年患者应用抗感染药物的合理性评价  

Rationality Appraisal of the Application of Anti-infective Drugs to768Elderly Patients

作　　者：纪莎[1] 胡雯玲[1] 

机构地区：[1]福建省中医学院附属第二人民医院,福州市350001

出　　处：《中国药房》2006年第15期1150-1152,共3页China Pharmacy

摘　　要：目的：探讨我院老年患者应用抗感染药物的合理性。方法：对我院2003年2004年768例老年患者应用抗感染药物情况进行回顾性调查与分析，并以世界卫生组织提出的限定日剂量（DDD）和药物利用指数（DUI）为依据，评价用药合理性。结果：抗感染药物的应用大多不合理，主要表现为首剂量偏大、疗程过长或过短及频繁换药。结论：在给予老年患者抗感染药物时，应根据其生理特性用药，特别是患有肝、肾功能障碍者更应引起重视。OBJECTIVE：To explore the rationality of applying anti-infective drugs to elderly patients.METHODS：Through retrospective investigation and analysis of 768 cases of anti - infective drugs application to elderly patients during 2003-2004, the rationality of drug application was appraised according to the DDD and DUI formulated by WHO.RESULTS： Most applications of anti - infective drugs were found to be irrational, which were manifested by a large first dose, an excessively long or short treatment course, or frequent changes of drugs.CONCLUSIONS： When anti- infective drugs are applied to elderly patients, the patients＇ physiological nature must be taken into consideration, especially for those with hepatic and renal function disturbance.

关 键 词：老年患者 抗感染药物 合理性 评价 

分 类 号：R978[医药卫生—药品]