年龄相关性黄斑病变患者晶体后囊混浊及脉络膜新生血管  

Posterior capsule opacity and choroidal neovascularization in patients ith age-related macular degeneration

作　　者：Rumelt S. Pollack A. 邢咏新(译) 

机构地区：[1]不详 [2]Department of Ophthalmology, Western Galilee-Nahariya Medical Center, P.O. Box 21, 22100 Nahariya, Israel

出　　处：《世界核心医学期刊文摘（眼科学分册）》2006年第6期36-36,共1页Digest of the World Core Medical Journals:Ophthalmology

摘　　要：BACKGROUND AND OBJECTIVE: To present a series of 3 patients with the dry form of age-related macular degeneration (AMD) in whom choroidal neovascularization (CNV) was observed following neodymium: yttrium-aluminum-garnet (Nd:YAG) capsulotomy. PATIENTS AND METHODS: Three consecutive patients aged 80 to 87 years (average=83.7 years) with hard drusen or retinal pigment epithelial changes underwent uneventful cataract extraction between 6 months and 20 years before undergoing Nd:YAG capsulotomy for posterior capsule opacity. The patients were examined for retinal changes before laser treatment and at regular intervals after treatment. RESULTS: All patients developed CNV between 12 days and 1 month after capsulotomy that caused a decrease in the visual acuity from 20/20-20/40 to 20/200-counting fingers at 4 feet. The fellow eye did not show a substantial change in AMD over a year of follow-up. Two of the fellow eyes had disci form scar due to CNV before the cataract surgery,and these patients remained legally blind. CONCLUSIONS: The development of CNV after Nd:YAG capsulotomy suggests a temporal association between the two and calls for further study. Because posterior capsule opacity may mask CNV,patients with dry AMD and posterior capsule opacity who experience decreased visual acuity or glare may undergo indocyanine green angiography before it is decided to perform Nd:YAG capsulotomy.BACKGROUND AND OBJECTIVE： To present a series of 3 patients with the dry form of age-related macular degeneration （AMD） in whom choroidal neovascularization （CNV） was observed following neodymium： yttrium-aluminumgarnet （Nd： YAG） capsulotomy. PATIENTS AND METHODS： Three consecutive patients aged 80 to 87 years （average = 83.7 years） with hard drusen or retinal pigment epithelial changes underwent uneventful cataract extraction between 6 months and 20 years before undergoing Nd： YAG capsulotomy for posterior capsule opacity. The patients were examined for retinal changes before laser treatment and at regular intervals after treatment. RESULTS： All patients developed CNV between 12 days and 1 month after capsulotomy that caused a decrease in the visual acuity from 20/20 -20/ 40 to 20/200-counting fingers at 4 feet. The fellow eye did not show a substantial change in AMD over a year of follow-up. Two of the fellow eyes had disci form scar due to CNV before the cataract surgery, and these patients remained legally blind. CONCLUSIONS： The development of CNV after Nd： YAG capsulotomy suggests a temporal association between the two and calls for further study. Because posterior capsule opacity may mask CNV, patients with dry AMD and posterior capsule opacity who experience decreased visual acuity or glare may undergo indocyanine green angiography before it is decided to perform Nd： YAG capsulotomy.

关 键 词：年龄相关性黄斑病变 晶体后囊混浊 脉络膜新生血管 患者 视网膜色素上皮细胞 Nd:YAG 后囊切开术 白内障摘除术 血管造影检查 激光晶体 

分 类 号：R774.5[医药卫生—眼科] R779.66[医药卫生—临床医学]