甲状腺眼病的屈光改变(被疏忽的临床表现)  

Refractive change in thyroid eye disease (a neglected clinical sign)

作　　者：Chandrasekaran S. Petsoglou C. Billson F. A. R. Ghabrial 安胜(译) 

机构地区：[1]不详 [2]Sydney Oculoplastic Surgery, 229 Macquarie Street, Sydney, NSW2000, Australia

出　　处：《世界核心医学期刊文摘（眼科学分册）》2006年第6期60-60,共1页Digest of the World Core Medical Journals:Ophthalmology

摘　　要：Background/aims: The literature on refractive change in thyroid eye disease (TED) is limited. This study documents the refractive change in patients with TED undergoing orbital decompression. The authors propose possible mechanisms for their acquired refractive error. Methods: This is a retrospective observational case study of five patients with progressive TED. Their detailed eye examinations including refractive state preoperatively and postoperatively are presented. Results: An acquired hypermetropic shift with active TED before orbital decompression of up to 3.75D spherical equivalent refraction (SER) is reported in one patient. Post-orbital decompression,an induced myopic shift of between 1.00-2.50D SER for all patients is observed,noted to range from 1 day following surgery to up to 9 months,dependent on the availability of data. Axial length increased in two cases corresponding to postoperative myopic shift. Magnetic resonance imaging findings of one patient demonstrate flattening of the posterior pole as a cause of the acquired preoperative hypermetropia. Conclusions: TED has a significant effect on the refractive state of patients. The proposed mechanism of acquired hypermetropia relates to increased volume of orbital contents with flattening of the posterior globe. This is reversed with successful orbital decompression. Documentation of refractive error in all cases of progressive TED is recommended. Progressive acquired hypermetropiamay be suggestive of TED activity.Background/aims： The literature on refractive change in thyroid eye disease （TED） is limited. This study documents the refractive change in patients with TED undergoing orbital decompression. The authors propose possible mechanisms for their acquired refractive error. Methods： This is a retrospective observational case study of five patients with progressive TED. Their detailed eye examinations including refractive state preoperatively and postoperatively are presented. Results： An acquired hypermetropic shift with active TED before orbital decompression of up to 3.75D spherical equivalent refraction （SER） is reported in one patient. Post-orbital decompression, an induced myopic shift of between 1.00 - 2.50D SER for all patients is observed, noted to range from 1 day following surgery to up to 9 months, dependent on the availability of data. Axial length increased in two cases corresponding to postoperative myopic shift. Magnetic resonance imaging findings of one patient demonstrate flattening of the posterior pole as a cause of the acquired preoperative hypermetropia. Conclusions： TED has a significant effect on the refractive state of patients. The proposed mechanism of acquired hypermetropia relates to increased volume of orbital contents with flattening of the posterior globe. This is reversed with successful orbital decompression. Documentation of refractive error in all cases of progressive TED is recommended. Progressive acquired hypermetropiamay be suggestive of TED activity.

关 键 词：甲状腺眼病 屈光改变 临床表现 眼眶减压术 ED患者 疏忽 高度远视 发病机制 屈光不正 屈光状态 

分 类 号：R581.1[医药卫生—内分泌] R77[医药卫生—内科学]