原发性空蝶鞍综合征合并自发性脑脊液鼻漏(附2例临床分析)  

Spontaneous cerebrospinal fluid rhinorrhea complicated from primary empty sella syndromea report of 2 cases

作　　者：邹华[1] 林琳[1] 龚坚[1] 刘翔[1] 郑亿庆[1] 

机构地区：[1]中山大学附属第二医院耳鼻咽喉科,广州510120

出　　处：《中国中西医结合耳鼻咽喉科杂志》2006年第4期227-229,共3页Chinese Journal of Otorhinolaryngology in Integrative Medicine

摘　　要：目的讨论原发性空蝶鞍综合征与自发性脑脊液鼻漏的病理生理联系、诊断及治疗。方法2例原发性空蝶鞍综合征合并自发性脑脊液鼻漏患者,经鼻漏液检验、MRI和鼻内镜检查确诊,行鼻内镜脑脊液鼻漏修补术。结果均治愈,随访2年余无复发。结论原发性空蝶鞍综合征和自发性脑脊液鼻漏有紧密的病理生理联系,MRI对空蝶鞍有诊断意义,治疗方法首选经鼻内镜下修补。Objective To investigate the pathophysiological association of spontaneous cerebrospinal fluid rhinorrhea（SCFR） with primary empty sella syndrome （PESS） and to explore diagnostic and therapeutic procedures for the lesion. Methods The two cases with SCFR complicated from PESS were analyzed carefully with their clinical data. Their diagnosis was made based on the findings from assaying on the fluid of rhinorrhea, MRI on sinuses and nasal endoscopy. Then, they were treated by endoscopic surgical procedures to repair the fistula and followed up for more than two years. Results The two cases were all cured without lesion reoccurring by the end of following up period. Conclusions There is a close pathophysiological association of SCFR with PESS. MRI is valuable for the diagnosis of empty sella syndrome, and surgical repairing procdures should be the first choice of treatment for this kind of spontaneous cerebrospinal fluid rhinorrhea.

关 键 词：空蝶鞍综合征 脑脊液鼻漏 鼻内镜修补术 

分 类 号：R765[医药卫生—耳鼻咽喉科]