妊娠合并糖尿病与新生儿心肌受损相关性研究  

Study on the relationship between gestational diabets mellitus and myocardical damage of new-born

作　　者：李霞[1] 王少峰[1] 井文君[1] 

机构地区：[1]济南市妇幼保健院NICU,山东250001

出　　处：《中国优生与遗传杂志》2006年第8期63-64,共2页Chinese Journal of Birth Health & Heredity

摘　　要：目的探讨妊娠合并糖尿病与新生儿心肌损害的关系。方法将30例母亲妊娠合并糖尿病的新生儿设为实验组,并选择同期住院母亲无妊娠合并症,出生时无窒息史等的新生儿作为对照组,分别于生后48h检测血清α-羥丁酸脱氢酶(α-HBDH)、乳酸脱氢酶(LDH)、肌酸激酶(CK)、肌酸激酶同工酶(CK-MB)的活性,并作对比分析。结果实验组与对照组的心肌酶活性有显著性差异(P<0.01)。且随血糖水平升高,心肌酶有增高趋势。结论血清CK-MB作为监测母亲系妊娠合并糖尿病所导致新生儿心肌损害的生化指标特异性强。Objective： To explor the relationship between gestational diabets mellitus （GDM） and myocardical damage of new - berns. Methods： The cases were radomly devided into two groups： experimental group and control group. Myocardical enzyme （α - HBDH , LDH, CK, CK -MB） were detected after 48 hours of bern in 30 cases which mother had GDM, compared with 21 well born infants without birth asphyxia and their mother without GDM in the periods, then made the statistics analysis. Result： There were significant difference in the myocardical enzyme between the two groups （ P 〈 0.01 ）, and the higher of the blood glucose, the higher of the myocardical enzyme. Conclusion： The surveillance of serum CK - MB can be treated as a specific target in infants of ddiabetic mother with myocardical damage .

关 键 词：妊娠合并糖尿病 新生儿 心肌酶 

分 类 号：R714.25[医药卫生—妇产科学]