老年肺结核合并肺部真菌感染的临床及药敏研究  

The clinical characteristic of tuberculosis with fungus infection in old people and the significance of sensitivity test

作　　者：胡华[1] 林美英[1] 鞠云飞[1] 

机构地区：[1]山东省胸科医院,250013

出　　处：《临床肺科杂志》2006年第5期575-576,共2页Journal of Clinical Pulmonary Medicine

摘　　要：目的探讨老年肺结核合并肺部真菌感染的临床特点、药敏状况及治疗。方法对我院老年肺结核患者入院时行常规真菌检测并对其肺部真菌感染的相关基础疾病、病原菌分类、药敏状况及治疗结果进行统计分析。结果①老年肺结核合并肺部真菌感染病史长,均有基础疾病,均用过抗生素。②病原菌中以白色念珠菌为主,占76.8%。③临床常见白色念珠菌感染,耐药率低,仅2例对氟胞嘧啶耐药。④克柔假丝酵母菌对5种药物均有耐药菌株,光滑念珠菌对4种药物均有耐药菌株,二者的耐药率高。结论老年肺结核合并肺部真菌感染发病率高,入院行常规药敏检测,早期采用有效的治疗,预后良好。Objective To evaluate the clinical characteristic of tuberculosis with fungus infection in old people, and the significance of drug sensitivity test and therapy. Methods Results of fungus culture, basis disease and therapy in tuberculosis in old people were analyzed. Results The old people of tuberculosis always had long history of using antibiotic therapy and they were easily affected by fungus infection espeeially by eandida albieans （ 76.8% ）. The resistant rates were high in eandida glabrata and eandida kiusei, and were low in candida albicans. Conclusion Significance of drug sensitivity test is helpful making early diagnosis and therapy evaluation for tuberculosis with fungus infection in old people.

关 键 词：老年 肺结核 肺部真菌 药敏 

分 类 号：R521[医药卫生—内科学] R519[医药卫生—临床医学]