影响复苏后综合征患者救治结果相关因素分析  

Analysis of factors associated with the results of treatment of post-resuscitation syndrome

作　　者：彭翔[1] 梁子敬[1] 韩洁韵[1] 李道海[1] 郭伟[1] 

机构地区：[1]广州医学院第一附属医院急诊科,广东广州510120

出　　处：《中国热带医学》2006年第8期1424-1425,共2页China Tropical Medicine

摘　　要：目的分析复苏后综合征(PRS)患者的救治效果与相关因素,探讨其治疗措施,为提高心肺复苏(CPR)最终成功率提供参考。方法回顾79例PRS患者,按自主循环恢复(ROSC)时间分组,统计分析复苏患者的ROSC时间与受损脏器数及存活的关系、首发受损脏器与多发受损脏器分布。结果ROSC时间≤10min者比>10min者的病死率明显降低(P<0.01),存活组的ROSC时间较植物人组及死亡组ROSC时间明显缩短(P<0.01),首先发生损害的脏器以心脑最为常见,而最多受损害的脏器是大脑,其次是心、肺功能损害。死亡组人均受损脏器数较存活出院组的平均受损脏器数明显增多(P<0.05)。结论ROSC时间越长,PRS患者病死率越增高,平均受损脏器数也越多;ROSC时间在10min以内者病死率明显降低,衰竭脏器明显减少;尽可能缩短ROSC时间是提高PRS患者生存率最有效的途径。Objective To analyze the clinical features of pest - resuscitation syndrome（PRS） and explore the therapeutic measure and provide reference for enhancement of rate of cardiopulmonary resuscitation （CPR）. Methods 79 PRS cases were retrospectively analyzed, The patients were divided into different groups based on the return of spontaneous circulation ROSC）time. ROSC time, the relationship between the numbers of suffering organs and probability of surviving visceras, distribution of suffering visceras were observed, Results There were a lower fatality rate in the patients with ROSC time of ≤ 10min than those with the ROSC time of 〉 10min （ P 〈 0.01 ）. The ROSC time of the patients in the survival group was much shorter than that in the vegetable group and the death group （P 〈 0,01）. The most common suffering organs were brain, heart and lung. There were more injured organs in the death group than that in the survival group （ P 〈 0.05）. Conclusion The longer ROSC time is, the higher fatality rate will be and the more organs are survived. Shortening ROSC time as much as possible may be the most effective way to increase survival rate. Special attention should be paid to PRS. Endotoxin - inflammatory mediator treated simulraneously maybe can increase the survival rate of PRS.

关 键 词：心肺复苏(CPR) 复苏后综合征(PRS) 多器官功能障碍(MODS) 临床特点 

分 类 号：R605.974[医药卫生—急诊医学]