用硅烷偶联剂处理生物玻璃表面及其复合支架的制备  

SURFACE TREATMENT OF BIOGLASS WITH SILANE COUPLING AGENT AND ITS PREPARATION FOR COMPOSITE SCAFFOLDS

作　　者：王迎军[1] 赵营刚[1] 卢玲[2] 陈晓峰[1] 吴刚[1] 任力[1] 

机构地区：[1]华南理工大学生物材料研究所 [2]华南理工大学特种功能材料及其制备新技术教育部重点实验室

出　　处：《硅酸盐学报》2006年第7期836-841,共6页Journal of The Chinese Ceramic Society

基　　金：国家自然科学基金(50272021;50472054;50403023);国家973项目(2005CB623902);广东省自然科学基金(04205786;020898;04300428);中国博士后科学基金(2003033035)资助项目

摘　　要：为了改善溶胶–凝胶生物活性玻璃与高分子材料的相容性,用硅烷偶联剂氨丙基三乙氧基硅烷对生物活性玻璃进行表面处理,并用X射线光电子能谱对处理后的生物活性玻璃的表面进行元素分析。结果表明:偶联剂通过Si—O—Si键被引入到生物活性玻璃表面。用处理后的生物活性玻璃与壳聚糖–明胶复合制备了多孔支架。扫描电子显微镜观察发现:复合多孔支架的两相相容性好,界面结合紧密;支架的孔隙连通、排列规则。力学测试表明:改性后的溶胶–凝胶生物活性玻璃与壳聚糖–明胶制备的复合支架力学性能得到明显改善。In order to improve the interface compatibility of polymer and sol-gel bioglass, surface of bioglass was treated by 3-aminopropyl triethoxysilane. The element components of bioglass surface were analyzed by an X-ray photoelectron spectroscope. The results show that 3-aminopropyl triethoxysilane was grafted on the particle surface of bioglass through the Si-O-Si bond. The bioglass composite scaffolds were prepared through blending bioglass after treatment with chitosan-gelatin. Scanning electronic microscope observation shows that in composite scaffolds the micro particles of two material phases are uniformly dispersed in chitosan-gelatin and have good compatibility. The holes of scaffold are connected each other and aligned regularly. The mechanical properties of composite scaffolds from treated bioglass are improved obviously.

关 键 词：生物玻璃 硅烷偶联剂 氨丙基三乙氧基硅烷 表面处理 

分 类 号：TB33[一般工业技术—材料科学与工程]