吸入液中异丙托溴铵和苯扎氯铵的HPLC测定  

DETERMINATION OF IPRATROPIUM BROMIDE AND BENZALKONIUM CHLORIDE IN INHALATION BY HPLC

作　　者：汪洁[1] 

机构地区：[1]上海市药品检验所

出　　处：《中国医药工业杂志》1996年第9期413-415,共3页Chinese Journal of Pharmaceuticals

摘　　要：以阳离子交换色谱柱，用流动相０．０２ｍｏｌ／ＬＫＨ＿２ＰＯ＿４－乙腈（４５：５５），经高效液相色谱法测定爱喘乐吸入液中异丙托溴铵和苯扎氯铵的含量。方法灵敏、简便、重现性好，平均回收率分别为１０２．０％和９８．６％。The HPLC method was used for simultaneous determination of ipratropium bromide and benzalkonium chloride in Atrovent solution, using SCXcolumn. The mobile phase consisted of 0.02mol/L potassium dihydrogen phosphateacetonitrile(45:55),and UV detector at 210nm. The average recoveries of ipratropium bromide and benzalkonium chloride were 102.0% and 98.6% respectively. The method is accurate and simple.

关 键 词：药物 异丙托溴铵 苯扎氯铵 吸入液 高效液相色谱 

分 类 号：R974[医药卫生—药品]