18079例胆石病患者临床分析  

Clinical Analysis of 18 079 Cases of Chololithiasis: A Single Institution's Study

作　　者：孙百军[1] 崔乃强[2] 张西波[2] 李忠廉[2] 赵二鹏[2] 陈凌[2] 钟玉川[2] 程凡菊[2] 张浩[2] 孟震[2] 朱丽[2] 

机构地区：[1]北京武警总医院移植科 [2]天津市南开医院胆胰疾病中心

出　　处：《中国中西医结合外科杂志》2006年第4期324-327,共4页Chinese Journal of Surgery of Integrated Traditional and Western Medicine

摘　　要：目的：分析我院近6年所收治胆石病患者的临床特征。方法：根据中华医学会胆道外科学组制定的全国胆石病临床调查表，对我院6年期间（2000年1月-2005年12月）经手术治疗的18079例胆石病患者分为：胆囊结石组、胆总管结石组、肝内胆管结石组、胆囊＋胆总管结石组、胆总管＋肝内胆管结石组、胆囊＋肝内胆管结石组、胆囊＋胆总管＋肝内胆管结石组，进行分组统计。观察各组发病年龄、性别、职业、地域等回顾性临床流行病学资料，经计算机整理后应用SPSSIO．0进行统计分析。结果：胆囊结石的比例显著升高（81．77％），并随年龄增长而增加，胆囊结石病发病的高峰年龄为40～69岁，占胆囊结石总例数的76．8％；胆囊合并胆总管结石以及单纯胆总管结石的发病高峰年龄为70～79岁，占该两组病人数量的31．29％；肝内胆管结石的高发年龄为40～59岁，占该组的55．94％；胆囊合并肝内胆管结石的高峰年龄为60～69岁，明显高于全国的统计数字，与饮食习惯及人口老龄化关系密切。不同部位胆石病男女比例明显不同，女性患者构成比明显高于男性患者。结论：随着经济不断发展胆石病的病种构成已经发生明显变化。胆石病占我院住院病人的比例较高，其中胆囊结石的构成比明显高于其他部位的胆石病患者，所收治患者中在发病高峰年龄、性别、职业构成均存在显著性差异。Objective To analyze the clinical features of patients with cholelithiasis admitted in recent 6 years, as well as the changing tendency of the spectrum of cholelithiasis Methods According to the National Clinical Questionaire for Cholelithiasis designed by Biliary Surgery Section of Chinese Medical Association, clinical data of 18 079 patients （12 285 females and 5 794 males）, aged 18 to 96（average 56.32 ± 13.93） years, who underwent operation for cholelithiasis in our hospital between January 2000 and December 2005 were retrospectively analyzed. The lesion sites, occupation, and habitation of patients were also reviewed. Results Patients with cholelithiasis were predominant in hospitalized patients in this hospital, among whom the constituent ratio of cholecystolithiasis was obviously higher than cholelithiasis in other sites. Significant differences existed in the peak morbidity, age, sex and occupation. The proportion of cholecystolithiasis has increased significantly, and was accompanied with the increase of age. The peak morbidity age of cholecystolithiasis was 40 to 69, which was obviously high. The peak age of gallbladder stone combined with intrahepatic bile duct stones was 60 to 69, which was obviously higher than that in national-wide census. The ratio of male and female with cholelithiasis in difilerent site had obvious diversity. The constituent ratio of female was manifestly higher than that of the male. Condusion In recent years, the spectrum of cholelithiasis in China has changed significantly and close to that in Western counties.

关 键 词：胆石病 流行病学 胆囊结石 

分 类 号：R657.42[医药卫生—外科学]