多普勒超声联合母血VIP、NPY检测宫内胎羊缺氧  被引量:3

Doppler Ultrasonography Combined with NPY and VIP in Evaluation of Fetal Acute Hypoxia in Late-gestation Sheep

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作  者:陈秋月[1] 吕国荣[1] 李伯义[1] 王振华[1] 何韶铮[1] 金鹏[1] 苏瑞娟[1] 

机构地区:[1]福建医科大学附属第二医院B超室,福建省泉州市362000

出  处:《中国超声医学杂志》2006年第8期580-582,共3页Chinese Journal of Ultrasound in Medicine

基  金:福建医科大学校级科学研究发展基金项目(FJGXYNo.04023)

摘  要:目的探讨胎羊脐动脉搏动指数(UAPI)、静脉导管搏动指数(DVPI)、肾动脉搏动指数(RAPI)联合母羊血清神经肽Y(NPY)、血管活性肠肽(VIP)评估胎羊宫内缺氧的意义。方法实验组胎羊采用间断性脐带血流阻塞法(UCO),用多普勒超声测量实验组和对照组胎羊UAPI、RAPI、DVPI,测母羊血NPY和VIP浓度及胎羊血气分析。结果UCO后实验组胎羊氧分压(Pa O2)、pH下降,二氧化碳分压(PaCO2)、UAPI、DVPI、RAPI、VIP、NPY升高,VIP、NPY、血流动力学与血气及VIP、NPY与血流动力学有明显相关。结论血流动力学检查联合NPY、VIP评估胎羊宫内缺氧可能更有意义。Objective To study fetal sheep umbilical artery pulsatile index (UAPI), ductus venosus pulsatile index (DVPI), renal artery pulsatile index (RAPI) combined with pregnant sheep vasoactive intestinal peptide (VIP), neuropeptide Y (NPY) in evaluation of fetal hypoxemia. Methods Fetal Sheep were studied with intermittent umbilical cord occlusion (UCO) performed in the experimental animal groups. Fetal arterial blood for blood gas, pregnant venous blood for VIP and NPY, Doppler measurement were sampled or performed. Results Over the experimental period in UCO fetuses, value of PH or PaO2 was declined, PaCO2 was raised as well as Doppler PI and value of VIP, NPY. There was a strong correlation between Doppler PI, VIP, NPY and blood gas, as well as Doppler PI and VIP, NPY. Conclusions Doppler ultrasonography combined with NPY and VIP is more reliable in the evaluation of fetal sheep acute hypoxia.

关 键 词:多普勒超声 血流动力学 神经肽Y 血管活性肠肽 宫内缺氧 脐带血流阻塞法 

分 类 号:R445.1[医药卫生—影像医学与核医学] R722.12[医药卫生—诊断学]

 

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