无创经皮电刺激仪治疗OSAS的实验研究和临床疗效  

Experimental Study of Non-invasive Percutaneous Electrical Stimulator for Treatment of Obstructive Sleep Apnea Syndrome and Its Clinical Effect

作　　者：胡良冈[1] 徐晓梅[2] 龚永生[1] 范小芳[1] 王良兴[2] 

机构地区：[1]温州医学院肺心病研究室,温州325027 [2]温州医学院附属第一医院呼吸内科,温州325000

出　　处：《生物医学工程学杂志》2006年第4期852-855,共4页Journal of Biomedical Engineering

基　　金：浙江省医药卫生科学研究基金资助项目(2002A063);温州市科技计划项目(Y2004A080)

摘　　要：研究采用经皮双向电流脉冲刺激舌下颏舌肌作为治疗阻塞性睡眠呼吸暂停综合征(O bstructive sleepapnea syndrom e,O SA S)的一种新方法。采用多导睡眠图同步监测患者,当发生睡眠呼吸暂停时及时给予最佳参数的电刺激,使得以颏舌肌为主的上气道扩张肌促使舌体向前运动,扩大舌咽气道,降低上气道阻力,改善夜间低氧血症,改善睡眠结构。临床疗效结果表明,22名O SA S患者经我们治疗后显效17名,好转2名,无效3名,有效率77.27%。初步证明这是一种的治疗O SA S的新方法。To study the stimulation of the genioglossus with percutaneous biphasic current pulses as a new therapeutical method to treat the obstructive sleep apnea syndrome （OSAS）, polysomnography （PSG） was used to synchronously monitor the patient. When OSAS was occurring, the stimulation with the optimal parameter was given in time to make the tongue move forward, the glossopharyngeal airway dilated, the resistance of the upper respiratory tract reduced, the hypoxia at night to be improved and the sleeping structure to be ameliorated because of the function of the dilated muscle of the upper airway. The results of the clinical therapeutic effect indicated that 17 of 22 patients with OSAS had eurstive effects, 2 of whom improved and 3 of whom were without effect. The effective rate was 77.27%. It is preliminarily proved that this is a new method in the treatment of patients suffered from OSAS.

关 键 词：阻塞性睡眠呼吸暂停综合征 经皮电刺激 睡眠医学 

分 类 号：R56[医药卫生—呼吸系统]