洗胃后立即灌注大剂量硫糖铝混悬液对上消化道出血的作用  

Effect of immediate abundant sucraffate suspension perfusion to prevent upper gastrointestinal hemorrhage after washing stomach

作　　者：武巧元[1] 马海鹰[1] 

机构地区：[1]南京中医药大学附属常州市中医医院急诊科(ICU),江苏省常州213003

出　　处：《中华急诊医学杂志》2006年第8期732-733,共2页Chinese Journal of Emergency Medicine

摘　　要：目的研究有机磷农药中毒洗胃后立即灌注大剂量硫糖铝混悬液预防上消化道出血的疗效。方法83例有机磷农药重度中毒患者随机分为2组,对照组40例在彻底洗胃后予西米替丁0．4静推,2次/ d,口服或鼻饲硫糖铝1．0/次,4次/d,连服5 d。治疗组在每次洗胃后胃管内立即注入硫糖铝3．0(研碎+温开水80ml),并同时辅以西米替丁、硫糖铝的常规治疗(同对照组)。结果治疗组在隐性出血、显性出血和住院时间上明显低于对照组(P＜0．05),但死亡率差异无显著性(P＞0．05)。结论有机磷农药中毒洗胃后立即灌注大剂量硫糖铝混悬液对预防上消化道出血及缩短住院时间上有明显疗效。Objective To study effect of immediate abundant sucralfate suspension perfusion to prevent upper gastrointestinal hemorrhage on the organophosphorous insecticides toxicosis suffer after washing stomach. Methods Total 83 patients suffering organophosphorous insecticides toxicosis were divided randomly into 2 groups randomly. In the control group, 40 samples were given cimetidine 0.4 g by vein injection after stomach washing completely twice one day. Meanwhile, they were taken sucralfate 1.0 g/ （4 times day） orally or by nastal feeding, continuing 5 days. In the treatment group, the samples were perfused sucralfate suspension 3,0 g （grind to powder, mixed with warm water 80 ml） by stomach tube after each stomach washing, and given routine treatment to assist （method as the control group）. Results In the aspects of recessive hemorrhage, conspicuous hemorrhage and hospitalizing period the treatment group was significant decreased compared with the control group （ P 〈 0.05）. However, Analysis of the results showed no significant difference in death rate （ P 〉 0.05 ）. Conclusion Immediate abundant sucralfate suspension perfusion after washing stomach has significant curative effect on preventing upper gastrointestinal hemorrhage and decreasing hospitalizing period.

关 键 词：有机磷农药中毒 硫糖铝 上消化道出血 

分 类 号：R595.4[医药卫生—内科学]