经颅多普勒监测克林澳对脑外伤后脑血管痉挛的治疗作用  

The therapentical effect of cinepazide meleate on posttraumatic vasospasm in patients with traumatic brain injury using transcranial Doppler.

作　　者：谢腾[1] 张捷[1] 袁先厚[1] 吴静[1] 江普查[1] 

机构地区：[1]武汉大学中南医院神经外科,武汉430071

出　　处：《华中医学杂志》2006年第4期307-308,共2页Central China Medical Journal

摘　　要：目的分析经颅多普勒(TCD)监测克林澳对脑外伤后脑血管痉挛(CVS)的治疗价值。方法将68例有症状并经TCD证实有CVS的轻、中型颅脑损伤患者分为克林澳治疗组(38例)和对照组(30例,刺五加治疗),治疗期间根据患者症状变化动态检测TCD,包括大脑中动脉(MCA)及椎动脉(VA)脑血流速度,分析克林澳对CVS的治疗效果。结果克林澳组血管痉挛的改善程度明显优于对照组,且CVS恢复正常所需时间也短于对照组(P<0.05)。结论TCD是监测CVS的有效方法,克林澳对脑血管痉挛及相关临床症状有明显的改善作用。Objective To analyze the effect of cinepazide meleate in treatment of cerebral vasospasm（CVS） using TCD. Methods A total of 68 patients of mitis and midrange craniocerebral injury with CVS were divided into two groups, the treatment group（n = 38, treated with cinepazide meleate） and the control group（n = 30, treated with a canthopancis senticosi）. Allthe patients have symptom and CVS confirmed by TCD, and detect the blood flow rate of MCA and VA. To analyze the effect of cinepazide meleate in treatment of CVS using TCD. Results CVS in the treatment group was improved with a higher improvement rate and with a shorter therapy period （P〈0. 05）. Conclusion TCD is an effective method to detect the CVS, and Cinepazide meleate is effective in the treatment of posttraumatic CVS.

关 键 词：脑血管痉挛 经颅多普勒 克林澳 

分 类 号：R651.15[医药卫生—外科学]