产前多疗程皮质类固醇激素应用现状  

The Application Status about Corticosteroid Treatment of More Courses in antepartum Condition

作　　者：陈贵岭[1] 成要平[1] 

机构地区：[1]山西医科大学第一附属医院,太原030001

出　　处：《医学综述》2006年第16期1006-1008,共3页Medical Recapitulate

摘　　要：早产是导致围生期新生儿死亡的主要原因。新生儿呼吸窘迫综合征(RDS)是危急早产儿生命的急性病。自皮质类固醇激素用于早产先兆的孕妇以来,它显著降低了新生儿RDS的发生率。但对有持续早产先兆的孕妇,产前多疗程皮质激素的应用对胎儿的潜在影响目前尚无临床试验研究(RCT)。目前的动物模型研究表明,产前重复应用皮质类固醇激素对胎儿肺、神经系统、免疫系统和内脏器官发育有负面影响。因此,产前重复激素治疗应权衡利弊。Premature delivery baby tends to suffer from the respiratory disu-ess syndrome （short for lIDS）, an acute and fatal disease. The BDS incident rate in newborn baby decreases significantly when eorticesteroid is applied to a pregnant woman who has threatened premature birth. But for a woman with the long time symptom of threatened premature birth, there is still no research of clinical test to prove that corticosteroid treatment of more will put a potential effect on the baby.Preecnt animal model indicates that the abuse of corticosteroid is harnfful to the development of baby＇s lung, immune system, and internal organs. Accordingly, eonicesteroid should be considered its positive and negative sides when we want to use it repeatedly.

关 键 词：早产 皮质类固醇 激素 肺成熟 

分 类 号：R714.05[医药卫生—妇产科学]