189例IgA肾病中、老年与青少年患者病理改变对比分析  

The pathological analysis of 189 IgA nephropathy cases in middle-senile and young patients

作　　者：栾森[1] 马行一[1] 胡章学[1] 杨立川[1] 张秀辉[1] 杨珉[1] 舒贝[1] 曾燕[1] 吴蔚桦[1] 

机构地区：[1]四川大学华西医院,四川成都610041

出　　处：《四川医学》2006年第8期776-777,共2页Sichuan Medical Journal

基　　金：国家自然科学基金(30270621)

摘　　要：目的对比分析IgA肾病中、老年(年龄>40岁)患者与青少年(年龄<40岁)患者病理改变特点。方法将我院189例经肾活检确诊为原发性IgA肾病患者分为中、老年和青少年两组,分别回顾性分析其病例组织光镜和免疫荧光检查的相关资料。结果在189例病理资料中,青少年组以轻度改变为主,免疫荧光检查以单纯IgA或C3沉积多见;而中老年组病例改变相对较重,中-重度改变者较多见,免疫荧光检查以单纯IgA或C3、IgA+IgM沉积较多。结论疑诊为IgA肾病的患者,尤其是老年人,应及时肾穿以利于早期诊断。Objective To observe the pathological features with the middle-senile and young patients. Methods 189 cases were divided into two groups according their ages. Their patholosical data were analied contrastively. Resuits As compared with young patients,the pathological characteristics of elderly patients were more seriously,and in immunofluorescence, the deposition of IgA,C3 or IgA ＋ IgM were more prominent. Conclusion The patients,especially the elder who are dougted to be IgA nephropathy should be ined with renal biopsy so as to help diagnose.

关 键 词：IGA肾病 病理 

分 类 号：R692.3[医药卫生—泌尿科学]