静脉注射胺碘酮与心律平转复阵发心房颤动的疗效比较  被引量:6

Comparison of the Effect of Amiodaron and Propafenone on Cardioversion of Paroxysmal Auricular Fibrillation

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作  者:李宗军[1] 王志[1] 

机构地区:[1]北京博爱医院急诊科,北京市100068

出  处:《中国康复理论与实践》2006年第7期608-609,共2页Chinese Journal of Rehabilitation Theory and Practice

摘  要:目的对比研究胺碘酮与心律平转复阵发心房颤动的疗效。方法阵发心房颤动(此次病程≤48h)患者58例随机分为两组:胺碘酮组30例,给予胺碘酮负荷量150mg静注后,继以0.6~1.0mg/min维持点滴,依心室率情况调整胺碘酮剂量。心律平组28例,静脉给予心律平1.4~2.0mg/kg,5min内注射,继以0.28mg/min维持静点,无效者改用胺碘酮治疗。结果胺碘酮组转复成功率为86.7%(26/30),心律平组转复成功率57.1%(16/28),且心律平组转复心律失败的部分病例使用胺碘酮仍有效;胺碘酮组平均复律时间(101±95)min(6~508min),心律平组(172±148)min(11~608min)。结论胺碘酮在转复阵发心房颤动比心律平更加快速、安全、有效。Objective To compare the effect of amiodaron and propafenone on the cardioversion of paroxysmal auricular fibrillation (PAF). Methods 58 PAF ( ≤48 h) cases were radomly divide into two groups: 30 cases who accepted amiodaron 150 mg intravenous injection, and 0.6~ 1.0 mg/min intravenous drip afterwards in amiodaron group, other 28 cases who accepted propafenone 1.4~2. 0 mg/kg vein injection, and 0.28 mg/min intravenous drip afterwards in propafenone group. If propafenone was not effective, the cases in propafenone group were given amidoaron. Results The successful reversion rate was 86.7 % (26/30) in amidoaron group while 57.1% (16/28) in propafenone group(P〈0.05). The mean time of recovering was (101 ± 95) min (6 ~508 min) in amidoaron group, while ( 172 ± 148) rain ( 11~ 608 min) in propafenone group(P〈0.05). Conclusion It is more rapid and effective of amidoaron on the cardloversion of paroxysmal auricular fibrillation than propafenone is.

关 键 词:心房纤维性颤动 胺碘酮 心律平 复律 

分 类 号:R541.7[医药卫生—心血管疾病]

 

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