^(99)锝-亚甲基二膦酸盐配合康复训练治疗强直性脊柱炎疗效观察  

Effect of ^(99)Tc-methylene Diphosphate Combined with Rehabilitation on Ankylosing Spondylitis

作　　者：陶杰梅[1] 张风肖[1] 孙丽君[1] 郑桂敏[1] 李芳[1] 宁晓然[1] 闫永龙[1] 

机构地区：[1]河北省人民医院风湿免疫科,河北石家庄市050051

出　　处：《中国康复理论与实践》2006年第7期622-623,共2页Chinese Journal of Rehabilitation Theory and Practice

摘　　要：目的99锝-亚甲基二膦酸盐(云克)配合康复训练治疗强直性脊柱炎的疗效。方法118例强直性脊柱炎患者随机分为治疗组58例和对照组60例,治疗组除常规给予美洛昔康和柳氮磺吡啶外,静脉推注云克配合康复训练;对照组仅给予美洛昔康和柳氮磺吡啶,观察两组患者治疗前后相关临床和实验室指标的变化。结果经过2个疗程治疗,治疗组在缓解关节疼痛、缩短晨僵时间、改善脊柱活动度、降低急性炎症指标ESR、CRP和PLT以及免疫球蛋白IgM等方面均优于对照组(P<0.05~0.01),且无明显副作用。结论云克配合康复训练治疗强直性脊柱炎疗效明显。Objective To observe the effect of 99Tc_methylene diphosphate （^99 Tc-MDP, Yunke） combined with rehabilitation on ankylosing spondylitis （AS）. Methods 118 AS patients were randomly divided into the treatment group （n= 58） and control group （n= 60）. The treatment group was treated with meloxicam, sulfasalazine and vein injecting Yunke combined rehabilitation. The control group was treated only with meloxicam and sulfasalazine. The changes of both clinical and experimental indexes of two groups before and after treatment were analyzed. Results After two therapeutic courses, a much better result was obtained in the treatment group compared with the control group at the respects of releasing arthralgia, shortening morning stiffness, improving range of spinal motion, and decreasing the levels of ESR, CRP, PLT and IgM, ect （P〈0. 05 ～0. 01） without obvious side effects. Conclusion The effect of Yunke combined with rehabilitation on AS is evident.

关 键 词：脊柱炎 强直性 ^99锝-亚甲基二膦酸盐 康复训练 

分 类 号：R593.23[医药卫生—内科学]