原发性高血压患者动态脉压与肾损害的关系  

Relationship between dynamic pulse pressure and renal damage in patients with essential hypertension.

作　　者：侯春兰[1] 时代音[1] 付红侠[1] 

机构地区：[1]西安交通大学第二医院干部病房,西安710004

出　　处：《陕西医学杂志》2006年第8期945-946,956,共3页Shaanxi Medical Journal

摘　　要：目的：探讨原发性高血压患者动态脉压与肾损害的关系。方法：对60例原发性高血压患者进行动态血压监测，按动态脉压分为脉压〉60mmHg组（PP1组）30例和脉压在40～60mmHg之间组（PP2组）30例，并测定两组患者的血、尿β2-微球蛋白（β2-MG）、尿微量白蛋白（mAlb）及血尿素氮（BUN）、肌酐（Cr）。比较两组24h血压动态参数及血、尿β2-MG、尿mAlb、血BUN、Cr。结果：脉压〉60mmHg组（PP1组）上述肾功能指标较脉压在40～60mmHg之间组（PP2组）升高（P〈0．01）。结论：原发性高血压患者肾损害与脉压增大有关。Objective： To investigate the relationship between dynamic pulse pressure and renal damage in essential hypertension. Methods： Sixty essential hypertensive patients were divided into two groups according to the levels of ambulatory pulse pressure（PP）. PP〉60mmHg （PP1 group） and 40mmHg ≤ PP ≤60mmHg （PP2group）. Ambulatory blood pressure monitoring, the serum and urine β2- MG, urine mAlb, blood BUN and Cr were measured in both groups and compared between two groups. Results： Compared with PP2 group, the PP1 group showed higher levels of renal function indexes （P〈0. 01）. Conclusion： Renal damage is related to pulse pressure in senile essential hypertension.

关 键 词：高血压/并发病 肾功能衰竭 @动态脉压 血压测定 

分 类 号：R544.1[医药卫生—心血管疾病] R587.1[医药卫生—内科学]