大孔树脂吸附纯化中药复方特性研究  

Studies on characteristics of absorption and separation of traditional Chinese medicine compound prescription by macroporous resin

作　　者：王高森[1] 侯世祥[1] 朱浩[1] 毛声俊[1] 毕岳琦[1] 

机构地区：[1]四川大学华西药学院,四川成都610041

出　　处：《中国中药杂志》2006年第15期1237-1240,共4页China Journal of Chinese Materia Medica

摘　　要：目的:研究复方中药吸附纯化的特性。方法:以一个含有生物碱、蒽醌、皂苷等由黄连、大黄、知母等药材组成的中药复方为样品,采用大孔树脂进行吸附纯化工艺和特性研究。结果:定性、定量研究证实,混煎复方中药中的主要有效成分或部位经过优化的工艺吸附纯化后,均可大部分保留。结论:若纯化工艺条件得当,同一型号的大孔吸附树脂能有效吸附纯化不同母核结构的复方中药有效成分或有效部位。Objective： Study the characteristics of absorption and separation of traditional Chinese medicine compound prescription using macroporous resin. Method： Study the techniquecs and characteristics of absorption and separation of a sample by macroporous resin,which is composed of coptis root, rhubard and contain anemarrhena rhizome; containing alkaloid, anthraquinone and saponin. Result： It is proved by qualitative and quantitative researches studies that after absorbed and separated by optimized, technicsprocess, most prime effective components or section fractions in traditional Chinese medicine compound prescription can be reservedmaintained. Conclusion： ff the techniquecs of separation is properly designed, the same kind of macropore resin can absorbd and separate various effective components or section in traditional Chinese medicine compound prescription which havewith different chemical structures efficiently.

关 键 词：大孔树脂 吸附纯化 中药复方 

分 类 号：R289[医药卫生—方剂学]